Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | CDC25B | P30305 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA7 | P43166 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | F2R | P25116 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.47 |
| ▸ | CDC25A | P30304 | 1/20 | 0.47 |
| ▸ | CDC25C | P30307 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL408906 | 0.85 | TSHR (0.74) | TSHRALDH1A1HSD17B10CDC25BKDM4E | |
| SCHEMBL8178343 | 0.84 | TSHR (0.61) | TSHRALDH1A1HSD17B10CDC25BCA12 | |
| SCHEMBL4626397 | 0.84 | TSHR (0.61) | TSHRALDH1A1HSD17B10CDC25BCA12 | |
| Bromide SCHEMBL15544606 | 0.84 | TSHR (0.71) | TSHRALDH1A1HSD17B10CDC25BKDM4E | |
| SCHEMBL28628629 | 0.84 | TSHR (0.71) | TSHRALDH1A1HSD17B10CDC25BKDM4E | |
| SCHEMBL18468247 | 0.84 | TSHR (0.55) | TSHRALDH1A1HSD17B10CA12CA1 | |
| SCHEMBL669621 | 0.83 | TSHR (0.59) | TSHRALDH1A1HSD17B10CDC25BCA12 | |
| SCHEMBL1188290 | 0.83 | ALDH1A1 (0.60) | TSHRALDH1A1HSD17B10CDC25BCA12 | |
| SCHEMBL27797134 | 0.83 | TSHR (0.59) | TSHRALDH1A1HSD17B10CDC25BCA12 | |
| SCHEMBL31257133 | 0.83 | TSHR (0.59) | TSHRALDH1A1HSD17B10CDC25BCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116730940-B | Heterocyclic substituted biphenyl compound and medical application thereof | 中国药科大学 | 2024-08-30 | — | — | CN | disclosed |
| CN-116730940-A | Heterocyclic substituted biphenyl compound and medical application thereof | 中国药科大学 | 2023-09-12 | — | — | CN | disclosed |
| CN-106458860-B | Pesticidal compositions and methods related thereto | 美国陶氏益农公司 | 2019-07-26 | — | — | CN | disclosed |
| CN-106165684-B | Pesticidal compositions and methods relating thereto | 陶氏益农公司 | 2019-06-14 | — | — | CN | disclosed |
| CN-105622496-B | Tetracycline compound | 四相制药公司 | 2019-03-05 | — | — | CN | disclosed |
| EP-3092240-B1 | ISOPROPYL TRIAZOLO PYRIDINE COMPOUNDS | LILLY CO ELI (US) | 2018-12-05 | — | — | EP | disclosed |
| CN-105025715-B | Pesticidal compositions and methods related thereto | 美国陶氏益农公司 | 2018-11-16 | — | — | CN | disclosed |
| CN-104981160-B | Pesticidal compositions and methods related thereto | 美国陶氏益农公司 | 2018-04-20 | — | — | CN | disclosed |
| CN-104981154-B | Pesticidal compositions and methods related thereto | 美国陶氏益农公司 | 2018-01-26 | — | — | CN | disclosed |
| CN-105899509-B | Isopropyl triazolopyridine compounds | 伊莱利利公司 | 2018-01-02 | — | — | CN | disclosed |
| WO-2005066139-A2 | 2-(AMINO-SUBSTITUTED)-4-ARYL PYRAMIDINES AND RELATED COMPOUNDS USEFUL FOR TREATING INFLAMMATORY DISEASES | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2005-07-21 | — | — | WO | disclosed |
| US-20030212094-A1 | Novel cyclic amide derivatives | MITSUBISHI PHARMA CORPORATION (JP) | 2003-11-13 | — | — | US | disclosed |
| EP-1260512-A1 | NOVEL CYCLIC AMIDE DERIVATIVES | Mitsubishi Pharma Corporation (JP) | 2002-11-27 | — | — | EP | disclosed |
| EP-0609798-B1 | 4-Benzoyl isoxazoles and their use as herbicides | AVENTIS AGRICULTURE LTD (GB) | 2002-10-02 | — | — | EP | disclosed |
| CN-1082790-C | Herbicides | RHONE POULENE AGRICULTURE LTD (GB) | 2002-04-17 | — | — | CN | disclosed |
| EP-0625505-B1 | 2-Cyano-1,3-dione derivatives and their use as herbicides | RHONE POULENC AGRICULTURE (GB) | 1998-10-28 | — | — | EP | disclosed |
| CN-1100261-A | Herbicides | RHONE POULENC AGRICULTURE (GB) | 1995-03-22 | — | — | CN | disclosed |
| US-5374606-A | Pre- and postemergence | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1994-12-20 | — | — | US | disclosed |
| EP-0625505-A2 | 2-Cyano-1,3-dione derivatives and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-11-23 | — | — | EP | disclosed |
| EP-0609798-A1 | 4-Benzoyl isoxazoles and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-08-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030212094-A1 | Novel cyclic amide derivatives | SIGMAR1, OPRM1, OPRD1 | TSHR 332/4885ALDH1A1 690/4885HSD17B10 907/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.