Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | LSS | P48449 | 3/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19865673 | 0.86 | MAPT (0.45) | KIF11NR1H2NR1H3LMNAMAPT | |
| SCHEMBL4089138 | 0.85 | MLYCD (0.42) | KIF11LSSHTR7NR1H2NR1H3 | |
| SCHEMBL13261444 | 0.84 | MAPT (0.46) | KIF11NR1H2NR1H3LMNAMAPT | |
| SCHEMBL15362902 | 0.82 | MAPT (0.51) | KIF11NR1H2NR1H3LMNAMAPT | |
| SCHEMBL5539693 | 0.81 | KIF11 (0.39) | KIF11NR1H2NR1H3LMNAMAPT | |
| SCHEMBL13223821 | 0.80 | SLC6A4 (0.37) | KIF11NR1H2NR1H3LMNAMAPT | |
| SCHEMBL13724695 | 0.80 | KIF11 (0.43) | PTPN1GSK3BKIF11NR1H2NR1H3 | |
| SCHEMBL20284303 | 0.78 | KIF11 (0.42) | KIF11NR1H2NR1H3MAPTPYCR1 | |
| SCHEMBL10499479 | 0.77 | MAPT (0.38) | PTPN1HTR7LMNAMAPT | |
| SCHEMBL5539145 | 0.77 | KIF11 (0.41) | KIF11NR1H2NR1H3PYCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090197201-A1 | FLUOROSURFACTANTS | MERCK PATENT GESELLSCHAFT (DE) | 2009-08-06 | — | — | US | disclosed |
| EP-2035129-A1 | FLUOROSURFACTANTS | Merck Patent GmbH (DE) | 2009-03-18 | — | — | EP | disclosed |
| WO-2008003443-A1 | FLUOROSURFACTANTS | MERCK PATENT GMBH (DE) | 2008-01-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090197201-A1 | FLUOROSURFACTANTS | CBR3, SCO2, FPR3 | PTPN1 2436/4885GSK3B 4138/4885SIRT2 1359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.