Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.71 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | MMP1 | P03956 | 1/20 | 0.55 |
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4082864 | 0.89 | PDE4B (0.86) | PDE4BHDAC8HDAC1MAPTNPC1 | |
| SCHEMBL3171960 | 0.86 | PDE4B (0.79) | PDE4BHDAC8HDAC1MAPTNPC1 | |
| SCHEMBL7924690 | 0.83 | PDE4B (0.66) | PDE4BHDAC8HDAC1MAPTNPC1 | |
| SCHEMBL99448 | 0.83 | PDE4B (1.00) | PDE4BHDAC8HDAC1MAPTNPC1 | |
| SCHEMBL7995333 | 0.83 | PDE4B (0.75) | PDE4BHDAC8HDAC1MAPTNPC1 | |
| SCHEMBL14960046 | 0.83 | PDE4B (0.75) | PDE4BHDAC8HDAC1MAPTNPC1 | |
| SCHEMBL20382586 | 0.82 | CA1 (0.53) | PDE4BHDAC8HDAC1MAPTNPC1 | |
| SCHEMBL16552644 | 0.82 | MMP1 (0.76) | PDE4BHDAC8HDAC1MAPTNPC1 | |
| SCHEMBL9541227 | 0.81 | PDE4B (0.73) | PDE4BHDAC8HDAC1MAPTNPC1 | |
| SCHEMBL31618944 | 0.81 | MAPT (0.46) | PDE4BHDAC8HDAC1MAPTGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090163743-A1 | LUMINESCENCE SYSTEM, METHOD OF LUMINESCENCE, AND CHEMICAL SUBSTANCE FOR LUMINESCENCE | HOSHI YOUSUKE | 2009-06-25 | — | — | US | disclosed |
| US-20070138945-A1 | Luminescence system, method of luminescence, and chemical substance for luminescence | HITACHI CHIEMICAL CO., LTD., (JP) | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070138945-A1 | Luminescence system, method of luminescence, and chemical substance for luminescence | GLO1, TYR, GUSB | PDE4B 854/4885HDAC8 4866/4885HDAC1 4836/4885 |
| US-20090163743-A1 | LUMINESCENCE SYSTEM, METHOD OF LUMINESCENCE, AND CHEMICAL SUBSTANCE FOR LUMINESCENCE | GLO1, TYR, GUSB | PDE4B 854/4885HDAC8 4866/4885HDAC1 4836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.