Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 2/20 | 0.32 |
| ▸ | GIPR | P48546 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.31 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.31 |
| ▸ | VIPR2 | P41587 | 1/20 | 0.31 |
| ▸ | GLP1R | P43220 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.30 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.30 |
| ▸ | EP300 | Q09472 | 3/20 | 0.30 |
| ▸ | ILK | Q13418 | 1/20 | 0.30 |
| ▸ | PDE2A | O00408 | 3/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4089679 | 0.78 | HTR2A (0.33) | GCGRGIPRHTR2AHTR2CHTR2B | |
| SCHEMBL4089672 | 0.71 | TRPV3 (0.43) | HTR2AHTR2CHTR2BTRPV3MAP3K12 | |
| SCHEMBL4100199 | 0.70 | PPARD (0.45) | GCGRGIPRHTR2AHTR2CHTR2B | |
| SCHEMBL3202062 | 0.69 | HTR2A (0.41) | HTR2AHTR2CHTR2BTRPV3HDAC6 | |
| SCHEMBL4094981 | 0.69 | TRPV3 (0.41) | HTR2AHTR2CHTR2BTRPV3MAP3K12 | |
| SCHEMBL24742426 | 0.69 | PPARD (0.38) | GCGRGIPR | |
| SCHEMBL12648301 | 0.69 | PPARD (0.38) | GCGRGIPR | |
| SCHEMBL30003505 | 0.69 | PPARD (0.38) | GCGRGIPR | |
| SCHEMBL1765886 | 0.69 | PPARA (0.48) | — | |
| SCHEMBL4104227 | 0.68 | PPARD (0.37) | GCGRGIPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090240058-A1 | Activator for Peroxisome Proliferator-Activating Receptor Delta | NIPPON CHEMIPHAR CO., LTD. (JP) | 2009-09-24 | — | — | US | disclosed |
| EP-1854784-A1 | ACTIVATOR FOR PEROXISOME PROLIFERATOR ACTIVATING RECEPTOR | Nippon Chemiphar Co., Ltd. (JP) | 2007-11-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090240058-A1 | Activator for Peroxisome Proliferator-Activating Receptor Delta | PPARG, PPARA, PPARD | GCGR 88/4885GIPR 546/4885HTR2A 2656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.