Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 3/20 | 0.33 |
| ▸ | BLM | P54132 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL910695 | 0.81 | L3MBTL1 (0.59) | MAPTL3MBTL1NPSR1ATMKDM4E | |
| SCHEMBL4090252 | 0.81 | L3MBTL1 (0.38) | MAPTL3MBTL1NPSR1HPGDSMN1; SMN2 | |
| SCHEMBL4090048 | 0.81 | L3MBTL1 (0.42) | MAPTL3MBTL1NPSR1HPGDSMN1; SMN2 | |
| SCHEMBL7123270 | 0.78 | HTR1A (0.61) | MAPTL3MBTL1HPGDHTR1ADRD2 | |
| SCHEMBL910377 | 0.78 | L3MBTL1 (0.51) | MAPTL3MBTL1NPSR1HPGDSMN1; SMN2 | |
| SCHEMBL3202776 | 0.77 | CYP1A2 (0.51) | MAPTL3MBTL1NPSR1HPGDATM | |
| SCHEMBL8943839 | 0.77 | L3MBTL1 (0.61) | MAPTL3MBTL1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL513917 | 0.77 | SLC6A2 (0.42) | MAPTL3MBTL1NPSR1SMN1; SMN2KDM4E | |
| SCHEMBL188509 | 0.76 | TAAR1 (0.57) | MAPTL3MBTL1HPGDKDM4EALDH1A1 | |
| SCHEMBL9260429 | 0.74 | MAPT (0.51) | MAPTL3MBTL1NPSR1HPGDATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090170131-A1 | Agents for Imaging Apoptosis | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2009-07-02 | — | — | US | disclosed |