Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 8/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD5 | P21918 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | TSPO | P30536 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4090252 | 0.81 | L3MBTL1 (0.38) | L3MBTL1MAPTNPSR1DRD1DRD2 | |
| SCHEMBL4090053 | 0.81 | MAPT (0.38) | L3MBTL1MAPTNPSR1DRD2KDM4E | |
| SCHEMBL31391959 | 0.81 | ALDH1A1 (0.41) | L3MBTL1MAPTNPSR1DRD1DRD2 | |
| SCHEMBL910695 | 0.81 | L3MBTL1 (0.59) | L3MBTL1MAPTNPSR1KDM4ETDP1 | |
| SCHEMBL513917 | 0.80 | SLC6A2 (0.42) | L3MBTL1MAPTNPSR1KDM4ESMN1; SMN2 | |
| SCHEMBL910377 | 0.78 | L3MBTL1 (0.51) | L3MBTL1MAPTNPSR1DRD1DRD2 | |
| SCHEMBL7123270 | 0.78 | HTR1A (0.61) | L3MBTL1MAPTDRD2KDM4EHPGD | |
| SCHEMBL7662939 | 0.78 | L3MBTL1 (0.46) | L3MBTL1MAPTNPSR1DRD1DRD2 | |
| SCHEMBL15576954 | 0.78 | L3MBTL1 (0.66) | L3MBTL1MAPTNPSR1DRD1DRD2 | |
| SCHEMBL8943839 | 0.77 | L3MBTL1 (0.61) | L3MBTL1MAPTKDM4EHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090170131-A1 | Agents for Imaging Apoptosis | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2009-07-02 | — | — | US | disclosed |