SCHEMBL4090250

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21542302	0.81	MEN1 (0.54)	PRSS1F2PRSS2PRSS3TMPRSS6
	SCHEMBL4089144	0.81	CDK1 (0.50)	PRSS1F2PRSS2PRSS3TMPRSS6
	SCHEMBL11935031	0.81	TAAR1 (0.46)	PRSS1F2PRSS2PRSS3TMPRSS6
	SCHEMBL2099205	0.81	HDAC1 (0.44)	PRSS1F2PRSS2PRSS3TMPRSS6
	SCHEMBL2090400	0.79	MEN1 (0.42)	PRSS1F2PRSS2PRSS3TMPRSS6
	SCHEMBL6236337	0.79	MEN1 (0.55)	HDAC1RHOCRHOAKIF11EPHX2
	SCHEMBL11108754	0.77	RHOC (0.46)	HDAC1RHOCRHOAKIF11EPHX2
	SCHEMBL10499489	0.77	PRSS1 (0.52)	PRSS1F2PRSS2PRSS3TMPRSS6
	SCHEMBL10499969	0.77	PRSS1 (0.52)	PRSS1F2PRSS2PRSS3TMPRSS6
	SCHEMBL8178051	0.77	MEN1 (0.61)	HDAC1RHOCRHOAKIF11EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.