SCHEMBL409084

SCHEMBL409084

COCCOC(=O)Oc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.56
BCL9 O00512 1/20 0.54
CTNNB1 P35222 1/20 0.54
GAA P10253 1/20 0.53
MAPT P10636 5/20 0.52
SMN1; SMN2 Q16637 3/20 0.49
ALDH1A1 P00352 2/20 0.49
LMNA P02545 1/20 0.49
TP53 P04637 1/20 0.49
CYP3A4 P08684 1/20 0.49
THRB P10828 1/20 0.49
MAPK1 P28482 1/20 0.49
HSD17B10 Q99714 1/20 0.49
MGLL Q99685 2/20 0.48
RAB9A P51151 2/20 0.47
KMT2A Q03164 2/20 0.47
NPC1 O15118 1/20 0.47
PKM P14618 1/20 0.46
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL40213 0.96 HTR2A (0.53) HTR2ABCL9CTNNB1GAAMAPT
SCHEMBL1104745 0.96 HTR2A (0.53) HTR2ABCL9CTNNB1GAAMAPT
SCHEMBL23044637 0.96 HTR2A (0.53) HTR2ABCL9CTNNB1GAAMAPT
SCHEMBL12082016 0.96 HTR2A (0.53) HTR2ABCL9CTNNB1GAAMAPT
SCHEMBL30233044 0.96 HTR2A (0.53) HTR2ABCL9CTNNB1GAAMAPT
SCHEMBL409598 0.92 HTR2A (0.59) HTR2ABCL9CTNNB1GAAMAPT
SCHEMBL9910888 0.91 HTR2A (0.54) HTR2ABCL9CTNNB1GAAMAPT
SCHEMBL14876975 0.91 HTR2A (0.54) HTR2ABCL9CTNNB1GAAMAPT
SCHEMBL4433836 0.88 HTR2A (0.56) HTR2ABCL9CTNNB1GAAMAPT
SCHEMBL125510 0.88 HTR2A (0.56) HTR2ABCL9CTNNB1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115161728-B Pore-forming agent for pore metallization, preparation method and application 南通赛可特电子有限公司 2023-10-20 CN claimed
CN-115161728-A Pore-finishing agent for pore metallization, preparation method and application 南通赛可特电子有限公司 2022-10-11 CN claimed
US-20150297681-A1 Pegylated Insulin Lispro Compounds ELI LILLY AND COMPANY (US) 2015-10-22 US claimed
EP-2288375-B1 PEGYLATED INSULIN LISPRO COMPOUNDS LILLY CO ELI (US) 2012-04-25 EP claimed
JP-2011524357-A 2011-09-01 JP claimed
US-20110105392-A1 Pegylated Insulin Lispro Compounds ELI LILLY AND COMPANY (US) 2011-05-05 US claimed
EP-2288375-A1 PEGYLATED INSULIN LISPRO COMPOUNDS ELI LILLY AND COMPANY (US) 2011-03-02 EP claimed
US-20090312236-A1 PEGYLATED INSULIN LISPRO COMPOUNDS ELI LILLY AND COMPANY 2009-12-17 US claimed
WO-2009152128-A1 PEGYLATED INSULIN LISPRO COMPOUNDS ELI LILLY AND COMPANY (US) 2009-12-17 WO claimed
WO-2024259930-A9 PHOSPHONATE COMPOUND AND MEDICAL USE THEREOF 润佳(苏州)医药科技有限公司 2025-04-24 WO disclosed
WO-2024259930-A1 PHOSPHONATE COMPOUND AND MEDICAL USE THEREOF 润佳(苏州)医药科技有限公司 2024-12-26 WO disclosed
CN-117285566-A Phosphonate compound and medical application thereof 润佳(苏州)医药科技有限公司 2023-12-26 CN disclosed
CN-112442011-B Prodrug compound and application thereof in treating cancers 润佳(苏州)医药科技有限公司 2023-11-14 CN disclosed
US-20230340011-A1 STEROIDAL COMPOSITIONS AND METHODS OF TREATING LIPOGENIC CANCERS Asteroid Therapeutics 2023-10-26 US disclosed
EP-1421175-A2 POLYMER STABILIZED PROTEINASES Mountain View Pharmaceuticals, Inc. (US) 2004-05-26 EP disclosed
WO-2004002985-A1 PEPTIDIC THROMBIN INHIBITOR COMPOUND LG LIFE SCIENCES LTD. (KR) 2004-01-08 WO disclosed
US-20030012777-A1 Polymer conjugates of proteinases MOUNTAIN VIEW PHARMACEUTICALS, INC. 2003-01-16 US disclosed
WO-2003002716-A2 POLYMER STABILIZED PROTEINASES MOUNTAIN VIEW PHARMACEUTICALS, INC. (US) 2003-01-09 WO disclosed
US-6291432-B1 (R)-N-(2-METHYLBENZYL)-3-((2S, 3S)-3-(N-(2-CHROMONECARBONYL)-L-ASPARAGINYL)AMINO-2-HYDROXY-4-PHENYLBUTANO YL)-5,5-DIMETHYL-1,3-THIAZOLIDINE-4-CARBOXAMIDE CAN BE GIVEN AS A TYPICAL EXAMPLE OF THIS COMPOUND. JAPAN ENERGY CORPORATION (JP) 2001-09-18 US disclosed
EP-0900566-A1 NOVEL TRIPEPTIDE COMPOUNDS AND ANTI-AIDS DRUGS JAPAN ENERGY CORPORATION (JP) 1999-03-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110105392-A1 Pegylated Insulin Lispro Compounds IAPP, IDE, LIPE HTR2A 3212/4885BCL9 4361/4885CTNNB1 4877/4885
US-20090312236-A1 PEGYLATED INSULIN LISPRO COMPOUNDS IAPP, IDE, LIPE HTR2A 3212/4885BCL9 4361/4885CTNNB1 4877/4885
US-20150297681-A1 Pegylated Insulin Lispro Compounds IAPP, IDE, LIPE HTR2A 3212/4885BCL9 4361/4885CTNNB1 4877/4885
US-20230340011-A1 STEROIDAL COMPOSITIONS AND METHODS OF TREATING LIPOGENIC CANCERS SREBF1, SREBF2, NR1H3 HTR2A 4484/4885BCL9 628/4885CTNNB1 509/4885
US-20030012777-A1 Polymer conjugates of proteinases PRNP, PRSS3, PRSS1 HTR2A 4693/4885BCL9 3968/4885CTNNB1 3917/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.