Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8508163 | 0.98 | MAPT (0.42) | MAPTHSD17B10MEN1KMT2AALOX12 | |
| SCHEMBL131605 | 0.84 | — | — | |
| SCHEMBL29764 | 0.84 | NPC1 (0.52) | MAPTHSD17B10MEN1KMT2AALOX15 | |
| SCHEMBL197157 | 0.84 | SNCA (0.50) | MAPTHSD17B10MEN1KMT2AALOX12 | |
| SCHEMBL14125018 | 0.83 | MAPT (0.37) | MAPTHSD17B10MEN1KMT2AALOX12 | |
| SCHEMBL12170048 | 0.81 | NPC1 (0.50) | MAPTHSD17B10MEN1KMT2AALOX15 | |
| SCHEMBL5889177 | 0.81 | SNCA (0.48) | MAPTHSD17B10MEN1KMT2AALOX12 | |
| SCHEMBL12982405 | 0.81 | NPC1 (0.50) | MAPTHSD17B10MEN1KMT2AALOX15 | |
| SCHEMBL120939 | 0.81 | NPC1 (0.50) | MAPTHSD17B10MEN1KMT2AALOX15 | |
| SCHEMBL5453288 | 0.81 | SNCA (0.48) | MAPTHSD17B10MEN1KMT2AALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2964704-B1 | HETEROCYCLIC FLUORESCENT DYES AND METHOD OF PRODUCTION THEREOF | BASF SE (DE) | 2018-05-16 | — | — | EP | disclosed |
| US-9893302-B2 | Heterocyclic fluorescent dyes and method of production thereof | BASF SE (DE) | 2018-02-13 | — | — | US | disclosed |
| US-20170133606-A1 | NOVEL HETEROCYCLIC FLUORESCENT DYES AND METHOD OF PRODUCTION THEREOF | CLAP CO., LTD. (KR) | 2017-05-11 | — | — | US | disclosed |
| US-20170133606-A1 | NOVEL HETEROCYCLIC FLUORESCENT DYES AND METHOD OF PRODUCTION THEREOF | CLAP CO., LTD. (KR) | 2017-05-11 | — | — | US | disclosed |
| US-9595680-B2 | Heterocyclic fluorescent dyes and method of production thereof | BASF SE (DE) | 2017-03-14 | — | — | US | disclosed |
| US-9595680-B2 | Heterocyclic fluorescent dyes and method of production thereof | BASF SE (DE) | 2017-03-14 | — | — | US | disclosed |
| US-9328127-B2 | System for controlling the reactivity of boronic acids | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2016-05-03 | — | — | US | disclosed |
| US-20150380660-A1 | NOVEL HETEROCYCLIC FLUORESCENT DYES AND METHOD OF PRODUCTION THEREOF | BASF SE (DE) | 2015-12-31 | — | — | US | disclosed |
| US-20150380660-A1 | NOVEL HETEROCYCLIC FLUORESCENT DYES AND METHOD OF PRODUCTION THEREOF | BASF SE (DE) | 2015-12-31 | — | — | US | disclosed |
| WO-2014135491-A1 | NOVEL HETEROCYCLIC FLUORESCENT DYES AND METHOD OF PRODUCTION THEREOF | BASF SE (DE) | 2014-09-12 | — | — | WO | disclosed |
| WO-2010107784-A1 | METHODS FOR ACTIVATION CONTROL OF PHOTOPOLYMERIZATION FOR HOLOGRAPHIC DATA STORAGE USING AT LEAST TWO WAVELENGTHS | STX APRILIS, INC. (US) | 2010-09-23 | — | — | WO | disclosed |
| US-20090069384-A1 | THIENOPYRROLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2009-03-12 | — | — | US | disclosed |
| EP-1946777-A1 | Substituted pyrazoline for preventing weight gain | Laboratorios del Dr. Esteve S.A. (ES) | 2008-07-23 | — | — | EP | disclosed |
| EP-1946778-A1 | Active substance combination for the treatment of diabetes | Laboratorios del Dr. Esteve S.A. (ES) | 2008-07-23 | — | — | EP | disclosed |
| EP-1844051-A1 | THIENOPYRROLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-17 | — | — | EP | disclosed |
| US-7262212-B2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-08-28 | — | — | US | disclosed |
| US-7262212-B2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-08-28 | — | — | US | disclosed |
| WO-2007009690-A1 | HETEROCYCLYL-SUBSTITUTED PYRAZOLINE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE, S.A (ES) | 2007-01-25 | — | — | WO | disclosed |
| EP-1743894-A1 | Heterocyclyl-substituted pyrazoline compounds, their preparation and use as medicaments | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-01-17 | — | — | EP | disclosed |
| WO-2006077412-A1 | THIENOPYRROLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150380660-A1 | NOVEL HETEROCYCLIC FLUORESCENT DYES AND METHOD OF PRODUCTION THEREOF | ORAI3, SLCO1B3, SLCO4C1 | MAPT 2456/4885HSD17B10 1227/4885MEN1 1137/4885 |
| US-20090069384-A1 | THIENOPYRROLES USEFUL IN THE TREATMENT OF INFLAMMATION | NPY5R, TH, PTGES | MAPT 54/4885HSD17B10 3431/4885MEN1 3153/4885 |
| US-20170133606-A1 | NOVEL HETEROCYCLIC FLUORESCENT DYES AND METHOD OF PRODUCTION THEREOF | ORAI3, SLCO1B3, SLCO4C1 | MAPT 2456/4885HSD17B10 1227/4885MEN1 1137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.