SCHEMBL197157

SCHEMBL197157

Brc1ccc(-c2ccc(Br)s2)s1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SNCA P37840 1/20 0.50
MAPT P10636 4/20 0.48
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
HSD17B10 Q99714 2/20 0.48
ALOX12 P18054 2/20 0.48
ALOX15 P16050 1/20 0.48
KDM4E B2RXH2 4/20 0.45
RAB9A P51151 3/20 0.45
SMN1; SMN2 Q16637 3/20 0.45
RXFP1 Q9HBX9 3/20 0.45
NPC1 O15118 2/20 0.45
ALDH1A1 P00352 2/20 0.45
PPARG P37231 2/20 0.45
NCOA2 Q15596 2/20 0.45
TP53 P04637 1/20 0.45
HPGD P15428 1/20 0.45
NCOA1 Q15788 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5889177 0.97 SNCA (0.48) SNCAMAPTMEN1KMT2AHSD17B10
SCHEMBL5889194 0.97 SNCA (0.48) SNCAMAPTMEN1KMT2AHSD17B10
SCHEMBL5453288 0.97 SNCA (0.48) SNCAMAPTMEN1KMT2AHSD17B10
SCHEMBL498474 0.97 SNCA (0.48) SNCAMAPTMEN1KMT2AHSD17B10
SCHEMBL16140274 0.88 SNCA (0.43) SNCAMAPTMEN1KMT2AHSD17B10
SCHEMBL2778388 0.84 SNCA (0.61) SNCAMAPTMEN1KMT2AHSD17B10
SCHEMBL4090912 0.84 MAPT (0.44) SNCAMAPTMEN1KMT2AHSD17B10
SCHEMBL3186391 0.84 MAPT (0.42) SNCAMAPTMEN1KMT2AHSD17B10
SCHEMBL13925222 0.84 SNCA (0.41) SNCAMAPTMEN1KMT2AHSD17B10
SCHEMBL28498819 0.84 SNCA (0.41) SNCAMAPTMEN1KMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 692 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025133616-A1 CONJUGATED POLYMER NANOPARTICLE BIOSENSORS STREAM BIO LTD (GB) 2025-06-26 WO claimed
CN-118173857-A Lithium-halogen-based double-ion battery taking sulfur/halogenated thiophene composite material as positive electrode 齐齐哈尔大学 2024-06-11 CN claimed
CN-118165205-A Dithiophene-based triazine polymer and preparation method thereof 桂林理工大学 2024-06-11 CN claimed
CN-118162110-A Preparation method of porous organic polymer material for adsorbing aflatoxin in vegetable oil and adsorption removal method 中国农业科学院油料作物研究所 2024-06-11 CN claimed
CN-112794994-B Thiophene unit-based porous organic polymer and preparation method and application thereof 辽宁大学 2023-09-15 CN claimed
CN-112794994-A Porous organic polymer based on thiophene unit and preparation method and application thereof 辽宁大学 2021-05-14 CN claimed
CN-109810244-A A kind of polythiofuran derivative photoelectric material and the preparation method and application thereof 华南理工大学 2019-05-28 CN claimed
US-20170043196-A1 Fire Extinguishing Composition Comprising Heterocyclic Compounds XI'AN J&R FIRE FIGHTING EQUIPMENT CO., LTD. (CN) 2017-02-16 US claimed
EP-3095485-A1 FIRE EXTINGUISHING COMPOSITION COMPRISING HETEROCYCLIC COMPOUNDS Xi'an J&R Fire Fighting Equipment Co., Ltd. (CN) 2016-11-23 EP claimed
EP-2482856-B1 MICELLAR COMPOSITIONS FOR USE IN BIOLOGICAL APPLICATIONS KING S COLLEGE LONDON (GB) 2015-07-08 EP claimed
CN-102627776-B Preparation method of chiral fluorescent nanoparticle based on hyperbranched conjugated polymer UNIV SOOCHOW 2014-09-17 CN claimed
US-20120269736-A1 MICELLAR COMPOSITIONS FOR USE IN BIOLOGICAL APPLICATIONS KING'S COLLEGE LONDON (GB) 2012-10-25 US claimed
EP-2482856-A2 MICELLAR COMPOSITIONS FOR USE IN BIOLOGICAL APPLICATIONS KINGS COLLEGE LONDON (GB) 2012-08-08 EP claimed
WO-2011039535-A2 MICELLAR COMPOSITIONS FOR USE IN BIOLOGICAL APPLICATIONS KING'S COLLEGE LONDON (GB) 2011-04-07 WO claimed
US-7906724-B2 N-type conjugated materials based on 2-vinyl-4,5-dicyanoimidazoles and their use in organic photovoltaics AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2011-03-15 US claimed
US-20090032106-A1 N-type conjugated materials based on 2-vinyl-4,5-dicyanoimidazoles and their use in organic photovoltaics AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH 2009-02-05 US claimed
US-20260013312-A1 PHOTOSENSITIVE ORGANIC INSULATING MATERIAL COMPOSITION, INSULATING FILM, GATE INSULATING FILM, TRANSISTOR, ELECTRONIC DEVICE, AND METHOD FOR MANUFACTURING TRANSISTOR NIKON CORPORATION (JP) 2026-01-08 US disclosed
CN-121248572-A Method for continuously synthesizing 5,5 '-dibromo-2, 2' -bithiophene through double-screw extrusion 西安近代化学研究所 2026-01-02 CN disclosed
EP-0624158-A1 ALKYLTHIOTHIOPHENES AND ALKYLTHIOPOLYTHIOPHENES, METHODS OF PREPARING THEM, AND THEIR USE BASF Aktiengesellschaft (DE) 1994-11-17 EP disclosed
WO-1993014079-A1 ALKYLTHIOTHIOPHENES AND ALKYLTHIOPOLYTHIOPHENES, METHODS OF PREPARING THEM, AND THEIR USE BASF AKTIENGESELLSCHAFT (DE) 1993-07-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090032106-A1 N-type conjugated materials based on 2-vinyl-4,5-dicyanoimidazoles and their use in organic photovoltaics NECTIN4, VCL, VDAC3 SNCA 2668/4885MAPT 1274/4885MEN1 2642/4885
US-20260013312-A1 PHOTOSENSITIVE ORGANIC INSULATING MATERIAL COMPOSITION, INSULATING FILM, GATE INSULATING FILM, TRANSISTOR, ELECTRONIC DEVICE, AND METHOD FOR MANUFACTURING TRANSISTOR ICMT, PIGT, PORCN SNCA 3726/4885MAPT 340/4885MEN1 315/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.