Known targets — ChEMBL curated mechanism
FGFR1FGFR2FGFR3FGFR4FLT1FLT4KDRPDGFRAPDGFRB
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29074312 | 0.90 | MAPT (0.37) | MAPTNPSR1MEN1APAF1NPC1 | |
| Sulfuric Acid SCHEMBL4539581 | 0.90 | MAPT (0.36) | MAPTNPSR1MEN1APAF1NPC1 | |
| Sulfuric Acid SCHEMBL15227677 | 0.88 | MAPT (0.38) | MAPTNPSR1MEN1APAF1NPC1 | |
| SCHEMBL408787 | 0.88 | MAPT (0.35) | MAPTNPSR1MEN1APAF1NPC1 | |
| Sulfuric Acid SCHEMBL1293162 | 0.86 | MAPT (0.34) | MAPTNPSR1MEN1APAF1NPC1 | |
| SCHEMBL412540 | 0.84 | MAPT (0.33) | MAPTNPSR1MEN1APAF1NPC1 | |
| SCHEMBL9935642 | 0.83 | FDPS (0.31) | FDPS | |
| Propane SCHEMBL29165671 | 0.83 | MEN1 (0.45) | MAPTNPSR1MEN1APAF1NPC1 | |
| SCHEMBL305714 | 0.82 | LMNA (0.33) | MAPTNPSR1MEN1APAF1NPC1 | |
| SCHEMBL9936316 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598593-B1 | USE OF IONIC LIQUIDS WITH A CONTENT OF IONIC POLYMERS | BASF SE (DE) | 2014-04-23 | — | — | EP | disclosed |
| US-8703670-B2 | Ionic liquids having a content of ionic polymers | BASF SE (DE) | 2014-04-22 | — | — | US | disclosed |
| US-20120021957-A1 | IONIC LIQUIDS HAVING A CONTENT OF IONIC POLYMERS | BASF SE (DE) | 2012-01-26 | — | — | US | disclosed |