SCHEMBL4091511

SCHEMBL4091511

COc1ccc(C(=O)c2ccc(OCCc3ccsc3)cc2)c(OC(C)(C)C(=O)O)c1

nearest known ligand 0.51

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PPARG P37231 12/20 0.51
PPARA Q07869 13/20 0.47
PPARD Q03181 11/20 0.47
NPC1 O15118 1/20 0.45
POLB P06746 1/20 0.41
MEN1 O00255 1/20 0.40
LMNA P02545 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
TSHR P16473 1/20 0.40
CYP2C19 P33261 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4097793 0.87 PPARG (0.64) PPARGPPARAPPARDNPC1POLB
Trifluoroacetic Acid SCHEMBL4108534 0.86 PPARG (0.38) PPARGPPARAPPARDNPC1POLB
SCHEMBL4099680 0.85 PPARG (0.55) PPARGPPARAPPARDNPC1MEN1
SCHEMBL4107824 0.84 NPC1 (0.58) PPARGPPARAPPARDNPC1POLB
SCHEMBL4097658 0.83 PPARA (0.59) PPARGPPARAPPARDNPC1
SCHEMBL4092953 0.83 PPARG (0.59) PPARGPPARAPPARDNPC1POLB
SCHEMBL4099824 0.83 PPARG (0.61) PPARGPPARAPPARDPOLB
SCHEMBL4097609 0.82 NPC1 (0.52) PPARGPPARAPPARDNPC1POLB
SCHEMBL4106819 0.80 PPARG (0.47) PPARGPPARAPPARDNPC1POLB
SCHEMBL4107394 0.79 PPARG (0.63) PPARGPPARAPPARDNPC1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090054435-A1 Phenoxyalkanoic Acid Compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-02-26 US disclosed
EP-1911738-A1 PHENOXYALKANOIC ACID COMPOUND Takeda Pharmaceutical Company Limited (JP) 2008-04-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054435-A1 Phenoxyalkanoic Acid Compound PNLIP, GPR119, LIPC PPARG 23/4885PPARA 8/4885PPARD 30/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.