SCHEMBL409160

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10189725	0.86	TP53 (0.34)	TUBB1TUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL411698	0.85	TUBB4A (0.56)	TUBB1TUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL411640	0.85	KDM4E (0.44)	TUBB1TUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL412607	0.84	TUBB1 (0.41)	TUBB1PTGS2TUBB4ATUBBTUBA3C
	SCHEMBL414049	0.84	ACHE (0.46)	TUBB1TUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL410428	0.84	FYN (0.48)	TUBB1TUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL411388	0.84	TUBB4A (0.54)	TUBB1TUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL13041108	0.84	KDR (0.52)	TUBB1TUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL413232	0.84	TUBB1 (0.40)	TUBB1PTGS2TUBB4ATUBBTUBA3C
	SCHEMBL14619539	0.83	KDM4E (0.56)	TUBB1TUBB4ATUBBTUBA3CTUBA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.