Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28118332 | 0.84 | ACHE (0.39) | POLBBBOX1ADRA2AADRA1AMAPT | |
| SCHEMBL18690258 | 0.81 | POLB (0.38) | POLBBBOX1ADRA2AADRA1AMAPT | |
| SCHEMBL16968101 | 0.78 | CHRM1 (0.42) | POLBADRA2AADRA1AMAPTBLM | |
| SCHEMBL28229885 | 0.76 | POLB (0.35) | POLBBBOX1 | |
| SCHEMBL28096337 | 0.75 | BBOX1 (0.33) | BBOX1 | |
| SCHEMBL18690265 | 0.73 | ACHE (0.41) | POLBBBOX1ADRA2AADRA1AMAPT | |
| SCHEMBL4091792 | 0.72 | POLB (0.39) | POLBBBOX1ADRA2AADRA1AMAPT | |
| Choline SCHEMBL2590257 | 0.70 | LMNA (0.52) | POLBBBOX1ADRA2AADRA1AMAPT | |
| SCHEMBL8169689 | 0.70 | POLB (0.37) | POLBBBOX1ADRA2AADRA1AMAPT | |
| SCHEMBL14743745 | 0.69 | BBOX1 (0.56) | POLBBBOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090208692-A1 | LIMITED LIFE OPTICAL MEDIA | FLEXPLAY TECHNOLOGIES, INC. (US) | 2009-08-20 | — | — | US | disclosed |