SCHEMBL4091801

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4086244	0.85	TP53 (0.48)	TP53ALDH1A1SMN1; SMN2NPC1RAB9A
	SCHEMBL4102719	0.83	TP53 (0.40)	TP53ALDH1A1SMN1; SMN2NPC1RAB9A
	SCHEMBL4092255	0.81	CA2 (0.40)	TP53ALDH1A1SMN1; SMN2NPC1RAB9A
	SCHEMBL4091003	0.80	KDM4E (0.43)	ALDH1A1SMN1; SMN2NPC1HSP90AA1PKM
	SCHEMBL4086376	0.80	TP53 (0.37)	TP53ALDH1A1SMN1; SMN2NPC1RAB9A
	SCHEMBL13928053	0.77	HSP90AA1 (0.56)	TP53ALDH1A1SMN1; SMN2NPC1RAB9A
	SCHEMBL4085571	0.74	NPC1 (0.42)	TP53ALDH1A1SMN1; SMN2NPC1TDP1
	SCHEMBL4093400	0.74	HSP90AA1 (0.46)	ALDH1A1SMN1; SMN2NPC1RAB9ATSHR
	SCHEMBL13928102	0.72	HTT (0.48)	ALDH1A1SMN1; SMN2TSHRHSP90AA1PKM
	SCHEMBL1808077	0.71	RAB9A (0.62)	ALDH1A1SMN1; SMN2NPC1RAB9ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.