Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | PTAFR | P25105 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4095792 | 0.89 | HSD17B1 (0.67) | HSD17B1LMNACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL4094282 | 0.81 | HSD17B1 (0.77) | HSD17B1LMNACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL4102391 | 0.79 | NR1H4 (0.60) | HSD17B1LMNAL3MBTL1ALDH1A1GAA | |
| SCHEMBL4090683 | 0.78 | PKM (0.51) | HSD17B1LMNACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL4100708 | 0.77 | HSD17B1 (0.62) | HSD17B1LMNACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL4099539 | 0.74 | HSD17B1 (0.64) | HSD17B1L3MBTL1ALDH1A1USP2NPSR1 | |
| SCHEMBL4091874 | 0.73 | HSD17B1 (0.78) | HSD17B1LMNACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL4092400 | 0.72 | HSD17B1 (0.66) | HSD17B1LMNAHSD17B10KDM4EGAA | |
| SCHEMBL4085974 | 0.71 | HSD17B1 (0.52) | HSD17B1CYP1A2CYP3A4CYP2C19L3MBTL1 | |
| SCHEMBL4092430 | 0.71 | NR1H4 (0.61) | LMNAL3MBTL1ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090186900-A1 | COMPOUND | STERIX LIMITED (GB) | 2009-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090186900-A1 | COMPOUND | HSD17B2, HSD17B11, CYP17A1 | HSD17B1 4/4885LMNA 1964/4885CYP1A2 38/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.