Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 2/20 | 0.49 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3160853 | 0.91 | ITGA4 (0.42) | ITGA4ITGB7MAPTTDP1NPSR1 | |
| SCHEMBL7439390 | 0.87 | ITGA4 (0.53) | ITGA4ITGB7MAPTTDP1POLB | |
| SCHEMBL6600210 | 0.87 | ITGA4 (0.53) | ITGA4ITGB7MAPTTDP1POLB | |
| SCHEMBL7439396 | 0.87 | ITGA4 (0.53) | ITGA4ITGB7MAPTTDP1POLB | |
| SCHEMBL3161587 | 0.83 | ITGA4 (0.42) | ITGA4ITGB7MAPTTDP1POLB | |
| SCHEMBL6428127 | 0.81 | ITGA4 (0.62) | ITGA4ITGB7MAPTTDP1POLB | |
| SCHEMBL7428724 | 0.80 | ITGA4 (0.59) | ITGA4ITGB7MAPTTDP1POLB | |
| SCHEMBL7428720 | 0.80 | ITGA4 (0.59) | ITGA4ITGB7MAPTTDP1POLB | |
| SCHEMBL4022463 | 0.78 | ITGA4 (0.58) | ITGA4ITGB7MAPTTDP1POLB | |
| SCHEMBL4022466 | 0.78 | ITGA4 (0.58) | ITGA4ITGB7MAPTTDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450301-B2 | Piperazine compounds with a herbicidal action | BASF SE (DE) | 2013-05-28 | — | — | US | disclosed |
| US-20090156553-A1 | PIPERAZINE COMPOUNDS WITH A HERBICIDAL ACTION | BASF SE (DE) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156553-A1 | PIPERAZINE COMPOUNDS WITH A HERBICIDAL ACTION | DDT, CAT, CIP2A | ITGA4 4796/4885ITGB7 4742/4885MAPT 3351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.