Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 2/20 | 0.42 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TACR1 | P25103 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | PTPRC | P08575 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 2/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4092239 | 0.91 | ITGA4 (0.49) | ITGA4ITGB7SCN9AMAPTTDP1 | |
| SCHEMBL7439396 | 0.83 | ITGA4 (0.53) | ITGA4ITGB7MAPTTDP1CTSS | |
| SCHEMBL7439390 | 0.83 | ITGA4 (0.53) | ITGA4ITGB7MAPTTDP1CTSS | |
| SCHEMBL6600210 | 0.83 | ITGA4 (0.53) | ITGA4ITGB7MAPTTDP1CTSS | |
| SCHEMBL3161587 | 0.81 | ITGA4 (0.42) | ITGA4ITGB7MAPTTDP1CTSS | |
| SCHEMBL585508 | 0.81 | SCN9A (0.42) | ITGA4ITGB7SCN9AMAPTTACR1 | |
| SCHEMBL3162028 | 0.79 | MMP8 (0.40) | MAPTTACR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL16001091 | 0.76 | TACR1 (0.50) | MAPTTACR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4092431 | 0.74 | MMP13 (0.39) | ITGA4ITGB7SCN9ATACR1L3MBTL1 | |
| SCHEMBL6428127 | 0.74 | ITGA4 (0.62) | ITGA4ITGB7MAPTTDP1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450301-B2 | Piperazine compounds with a herbicidal action | BASF SE (DE) | 2013-05-28 | — | — | US | disclosed |
| EP-1971580-B1 | PIPERAZINE COMPOUNDS WITH A HERBICIDAL ACTION | BASF SE (DE) | 2010-02-24 | — | — | EP | disclosed |
| US-20090156553-A1 | PIPERAZINE COMPOUNDS WITH A HERBICIDAL ACTION | BASF SE (DE) | 2009-06-18 | — | — | US | disclosed |
| EP-1971580-A1 | PIPERAZINE COMPOUNDS WITH A HERBICIDAL ACTION | BASF SE (DE) | 2008-09-24 | — | — | EP | disclosed |
| WO-2007077201-A9 | PIPERAZINE COMPOUNDS WITH A HERBICIDAL ACTION | BASF SE (DE) | 2008-07-31 | — | — | WO | disclosed |
| WO-2007077201-A1 | PIPERAZINE COMPOUNDS WITH A HERBICIDAL ACTION | BASF SE (DE) | 2007-07-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156553-A1 | PIPERAZINE COMPOUNDS WITH A HERBICIDAL ACTION | DDT, CAT, CIP2A | ITGA4 4796/4885ITGB7 4742/4885SCN9A 3309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.