Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 8/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4103760 | 0.89 | STING1 (0.60) | STING1PARP14HSD17B10 | |
| SCHEMBL27144986 | 0.85 | MAPT (0.54) | STING1MAPTHPGDALDH1A1KDM4E | |
| SCHEMBL4099310 | 0.85 | STING1 (0.54) | STING1MAPTHPGDALDH1A1KDM4E | |
| SCHEMBL5142090 | 0.84 | STING1 (0.55) | STING1MAPTALDH1A1 | |
| SCHEMBL27522079 | 0.83 | STING1 (0.54) | STING1MAPTALDH1A1 | |
| SCHEMBL6455572 | 0.82 | CTNNB1 (0.63) | STING1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL22246551 | 0.81 | STING1 (0.70) | STING1PARP14MAPTALDH1A1KMT2A | |
| SCHEMBL28680990 | 0.81 | LMNA (0.50) | STING1MAPK1MAPTALDH1A1KDM4E | |
| SCHEMBL28681121 | 0.81 | NR4A2 (0.50) | STING1MAPK1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL1596152 | 0.80 | STING1 (0.61) | STING1PARP14MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113943244-B | Sulfur-containing gamma, gamma-diindolylbutyramide compounds prepared by difunctional reactions | 温州大学 | 2023-05-23 | — | — | CN | disclosed |
| CN-113943244-A | Sulfur-containing gamma, gamma-diindolyl butyramide compound prepared by double-functionalization reaction | 温州大学 | 2022-01-18 | — | — | CN | disclosed |
| US-9206156-B2 | Substituted indole derivatives | Grünenthal GmbH (DE) | 2015-12-08 | — | — | US | disclosed |
| US-20130116283-A1 | Substituted indole derivatives | Grünenthal GmbH (DE) | 2013-05-09 | — | — | US | disclosed |
| US-20090215828-A1 | Substituted indole derivatives | GRUNENTHAL GMBH (DE) | 2009-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215828-A1 | Substituted indole derivatives | IDO1, IDO2, TPH1 | STING1 961/4885MAPK1 3697/4885PARP14 889/4885 |
| US-20130116283-A1 | Substituted indole derivatives | IDO1, IDO2, TPH1 | STING1 961/4885MAPK1 3697/4885PARP14 889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.