Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 2/20 | 0.63 |
| ▸ | WNT3A | P56704 | 2/20 | 0.63 |
| ▸ | KDM1A | O60341 | 1/20 | 0.52 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | STING1 | Q86WV6 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4092376 | 0.82 | STING1 (0.59) | KDM1AALDH1A1STING1MAPTMEN1 | |
| SCHEMBL5142090 | 0.79 | STING1 (0.55) | ALDH1A1STING1MAPTGAALMNA | |
| SCHEMBL7543952 | 0.79 | STING1 (0.55) | STING1MAPTMEN1KMT2APKM | |
| SCHEMBL4103760 | 0.78 | STING1 (0.60) | STING1LMNA | |
| SCHEMBL27522079 | 0.78 | STING1 (0.54) | ALDH1A1STING1MAPTGAA | |
| SCHEMBL15969761 | 0.78 | CTNNB1 (1.00) | CTNNB1WNT3AKDM1AADAM17ALDH1A1 | |
| SCHEMBL4099310 | 0.78 | STING1 (0.54) | KDM1AALDH1A1STING1MAPTMEN1 | |
| SCHEMBL27144986 | 0.78 | MAPT (0.54) | KDM1AALDH1A1STING1MAPTMEN1 | |
| SCHEMBL384965 | 0.77 | STING1 (0.63) | STING1MEN1KMT2A | |
| SCHEMBL28736881 | 0.75 | STING1 (0.74) | ALDH1A1STING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050197350-A1 | Novel quinoline, tetrahydroquinazoline, and pyrimidine derivatives and methods of treatment related to the use thereof | TAISHO PHARMACEUTICAL CO., LTD. | 2005-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050197350-A1 | Novel quinoline, tetrahydroquinazoline, and pyrimidine derivatives and methods of treatment related to the use thereof | HCRTR2, MCHR1, MCHR2 | CTNNB1 4405/4885WNT3A 4118/4885KDM1A 1817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.