Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | AHR | P35869 | 1/20 | 0.51 |
| ▸ | CETP | P11597 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4241319 | 0.78 | SMN1; SMN2 (0.60) | ALDH1A1GAAALOX12MAPTMEN1 | |
| SCHEMBL4053350 | 0.78 | GAA (0.50) | NOTUMLMNAALDH1A1GAATP53 | |
| SCHEMBL7243115 | 0.76 | KCNH2 (0.68) | NOTUMLMNAALDH1A1GAATP53 | |
| SCHEMBL2554923 | 0.76 | NOTUM (0.60) | NOTUMLMNAALDH1A1GAATP53 | |
| SCHEMBL15847616 | 0.75 | SMN1; SMN2 (0.53) | NOTUMLMNAALDH1A1GAAMAPT | |
| SCHEMBL18328460 | 0.75 | NOTUM (0.65) | NOTUMLMNAALDH1A1GAATP53 | |
| SCHEMBL4293439 | 0.72 | RAB9A (0.70) | LMNAALDH1A1GAATP53ALOX12 | |
| SCHEMBL8428158 | 0.72 | GAA (0.58) | NOTUMLMNAALDH1A1GAATP53 | |
| SCHEMBL22227971 | 0.72 | ALDH1A1 (0.66) | NOTUMLMNAALDH1A1GAATP53 | |
| SCHEMBL30602658 | 0.72 | ALDH1A1 (0.66) | NOTUMLMNAALDH1A1GAATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1858540-A2 | STABILIZED COMPOSITIONS CONTAINING NATRIURETIC PEPTIDES | Bio-Rad Laboratories, Inc. (US) | 2007-11-28 | — | — | EP | claimed |
| WO-2006088624-A2 | STABILIZED COMPOSITIONS CONTAINING NATRIURETIC PEPTIDES | BIO-RAD LABORATORIES, INC. (US) | 2006-08-24 | — | — | WO | claimed |
| US-20060183681-A1 | Stabilized compositions containing natriuretic peptides | BIO-RAD LABORATORIES, INC. (US) | 2006-08-17 | — | — | US | claimed |
| US-20200158739-A1 | METHOD, COMPOSITION AND DEVICE FOR SAMPLING NATRIURETIC PEPTIDES IN A BIOLOGICAL FLUID | QUIDEL CORPORATION | 2020-05-21 | — | — | US | disclosed |
| US-10641781-B2 | Method, composition and device for sampling natriuretic peptides in a biological fluid | CRIMSON U.S. ASSETS LLC (US) | 2020-05-05 | — | — | US | disclosed |
| US-20170003305-A1 | METHOD, COMPOSITION AND DEVICE FOR SAMPLING NATRIURETIC PEPTIDES IN A BIOLOGICAL FLUID | CRIMSON U.S. ASSETS LLC (US) | 2017-01-05 | — | — | US | disclosed |
| US-9482677-B2 | Method, composition and device for sampling natriuretic peptides in a biological fluid | SCIOS INC. (US) | 2016-11-01 | — | — | US | disclosed |
| EP-2098866-B1 | Method, composition and device for sampling natriuretic peptides in a biological fluid | SCIOS INC (US) | 2013-05-01 | — | — | EP | disclosed |
| EP-2098866-A1 | Method, composition and device for sampling natriuretic peptides in a biological fluid | Scios Inc. (US) | 2009-09-09 | — | — | EP | disclosed |
| US-20090215182-A1 | METHOD, COMPOSITION AND DEVICE FOR SAMPLING NATRIURETIC PEPTIDES IN A BIOLOGICAL FLUID | QUIDEL CORPORATION | 2009-08-27 | — | — | US | disclosed |
| EP-1858540-A2 | STABILIZED COMPOSITIONS CONTAINING NATRIURETIC PEPTIDES | Bio-Rad Laboratories, Inc. (US) | 2007-11-28 | — | — | EP | disclosed |
| WO-2006088624-A2 | STABILIZED COMPOSITIONS CONTAINING NATRIURETIC PEPTIDES | BIO-RAD LABORATORIES, INC. (US) | 2006-08-24 | — | — | WO | disclosed |
| US-20060183681-A1 | Stabilized compositions containing natriuretic peptides | BIO-RAD LABORATORIES, INC. (US) | 2006-08-17 | — | — | US | disclosed |