Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | EYA3 | Q99504 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23430426 | 0.81 | VKORC1 (0.41) | PLK1KDM4EAHRVKORC1ABCB1 | |
| SCHEMBL718444 | 0.80 | ABCB1 (0.44) | PLK1KDM4EVKORC1ABCB1SLC22A12 | |
| SCHEMBL4092983 | 0.79 | L3MBTL1 (0.57) | KDM4EAHRL3MBTL1RECQLKMT2A | |
| SCHEMBL28131940 | 0.78 | TEAD1 (0.51) | PLK1KDM4EAHRCAPN1MEN1 | |
| SCHEMBL25854597 | 0.77 | ABCB1 (0.44) | PLK1KDM4EVKORC1ABCB1SLC22A12 | |
| SCHEMBL26506708 | 0.76 | ABCB1 (0.40) | PLK1KDM4EVKORC1ABCB1SLC22A12 | |
| SCHEMBL4773987 | 0.75 | EYA3 (0.47) | PLK1KDM4EAHRABCB1SLC22A12 | |
| Oxalic Acid SCHEMBL28849573 | 0.74 | ALDH1A1 (0.49) | PLK1KDM4EAHRL3MBTL1CAPN1 | |
| SCHEMBL4792448 | 0.74 | ABCB1 (0.38) | PLK1KDM4EVKORC1ABCB1SLC22A12 | |
| Sulfuric Acid SCHEMBL28171448 | 0.73 | KMT2A (0.47) | PLK1KDM4EAHRCAPN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156578-A1 | 3-Heterocyclylacrylamide Compounds as Fab I Inhibitors and Antibacterial Agents | DEBIOPHARM INTERNATIONAL SA (CH) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156578-A1 | 3-Heterocyclylacrylamide Compounds as Fab I Inhibitors and Antibacterial Agents | GAA, TFPI, DBI | PLK1 3315/4885KDM4E 3209/4885AHR 4212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.