Sugi Predict

Sugi Predict / Compounds / SCHEMBL4093041

SCHEMBL4093041

SCHEMBL4093041

CCOC(=O)c1csc(NC(=N)N)n1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP1A2 P05177 1/20 0.71
▸ CYP2C19 P33261 1/20 0.71
▸ SMN1; SMN2 Q16637 6/20 0.63
▸ RAB9A P51151 6/20 0.63
▸ NPC1 O15118 5/20 0.63
▸ TDP1 Q9NUW8 1/20 0.60
▸ GAA P10253 2/20 0.60
▸ MAPT P10636 2/20 0.59
▸ HSP90AA1 P07900 2/20 0.59
▸ MAPK1 P28482 1/20 0.59
▸ LMNA P02545 3/20 0.59
▸ NPSR1 Q6W5P4 1/20 0.59
▸ HSD17B10 Q99714 1/20 0.59
▸ ALDH1A1 P00352 3/20 0.57
▸ MEN1 O00255 1/20 0.57
▸ KMT2A Q03164 1/20 0.57
▸ KDM4E B2RXH2 3/20 0.57
▸ HPGD P15428 2/20 0.57
▸ TSHR P16473 1/20 0.57
▸ EGFR P00533 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL7142285 0.99 CYP1A2 (0.69) CYP1A2CYP2C19SMN1; SMN2RAB9ANPC1
SCHEMBL4871149 0.84 CYP1A2 (0.76) CYP1A2CYP2C19SMN1; SMN2RAB9ANPC1
SCHEMBL10863374 0.83 CYP1A2 (0.49) CYP1A2CYP2C19SMN1; SMN2RAB9ANPC1
SCHEMBL4564086 0.82 CYP1A2 (0.69) CYP1A2CYP2C19SMN1; SMN2RAB9ANPC1
SCHEMBL3603455 0.82 CYP1A2 (0.48) CYP1A2CYP2C19SMN1; SMN2RAB9ANPC1
Bromide SCHEMBL29010966 0.81 CYP1A2 (0.68) CYP1A2CYP2C19SMN1; SMN2RAB9ANPC1
SCHEMBL10975815 0.81 L3MBTL1 (0.46) CYP1A2CYP2C19SMN1; SMN2RAB9ANPC1
Bromide SCHEMBL17895414 0.81 CYP1A2 (0.68) CYP1A2CYP2C19SMN1; SMN2RAB9ANPC1
SCHEMBL1816233 0.81 CYP1A2 (0.71) CYP1A2CYP2C19SMN1; SMN2RAB9ANPC1
SCHEMBL4875411 0.81 CYP1A2 (0.71) CYP1A2CYP2C19SMN1; SMN2RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200140460-A1 ANTIBACTERIAL THERAPEUTICS AND PROPHYLACTICS VYOME BIOSCIENCES PVT. LTD. (IN) 2020-05-07 — — US disclosed
US-20200140460-A1 ANTIBACTERIAL THERAPEUTICS AND PROPHYLACTICS VYOME BIOSCIENCES PVT. LTD. (IN) 2020-05-07 — — US disclosed
US-10570152-B2 Antibacterial therapeutics and prophylactics VYOME THERAPEUTICS LIMITED (IN) 2020-02-25 — — US disclosed
US-10570152-B2 Antibacterial therapeutics and prophylactics VYOME THERAPEUTICS LIMITED (IN) 2020-02-25 — — US disclosed
US-20180265523-A1 ANTIBACTERIAL THERAPEUTICS AND PROPHYLACTICS VYOME THERAPEUTICS LIMITED (IN) 2018-09-20 — — US disclosed
EP-3328856-A2 ANTIBACTERIAL THERAPEUTICS AND PROPHYLACTICS Vyome Biosciences Pvt. Ltd. (IN) 2018-06-06 — — EP disclosed
WO-2017017631-A2 ANTIBACTERIAL THERAPEUTICS AND PROPHYLACTICS VYOME BIOSCIENCES PVT. LTD. (IN) 2017-02-02 — — WO disclosed
WO-2017017631-A2 ANTIBACTERIAL THERAPEUTICS AND PROPHYLACTICS VYOME BIOSCIENCES PVT. LTD. (IN) 2017-02-02 — — WO disclosed
US-20090194124-A1 Hair Shaping Kit and Process Comprising at Least One Non-Hydroxide Imine MALLE GERARD 2009-08-06 — — US disclosed
US-20090139537-A1 HAIR RELAXING COMPOSITION COMPRISING AT LEAST ONE NON-HYDROXIDE IMINE L'OREAL S.A. 2009-06-04 — — US disclosed
EP-0928790-A1 Thiazole derivatives F. HOFFMANN-LA ROCHE AG (CH) 1999-07-14 — — EP disclosed
US-4590299-A 2-guanidino-4-heteroarylthiazoles PFIZER INC. (US) 1986-05-20 — — US disclosed
US-4510313-A 2-Guanidino-4-heteroarylthiazoles PFIZER INC. (US) 1985-04-09 — — US disclosed
US-4492794-A 2-Guanidino-4-hydroxymethylthiazole and derivatives thereof SHIONOGI & CO., LTD. (JP) 1985-01-08 — — US disclosed
EP-0050458-B1 2-GUANIDINO-4-HETEROARYLTHIAZOLES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM PFIZER INC. (US) 1985-01-02 — — EP disclosed
EP-0123741-A1 2-Guanidino-4-hydroxymethylthiazole and derivatives thereof SHIONOGI & CO., LTD. (JP) 1984-11-07 — — EP disclosed
US-4452987-A Haloacetyl imidazoles PFIZER INC. (US) 1984-06-05 — — US disclosed
EP-0074229-A1 Triazole gastric anti-secretory agents PFIZER INC. (US) 1983-03-16 — — EP disclosed
US-4374843-A 2-Guanidino-4-heteroarylthiazoles PFIZER INC. (US) 1983-02-22 — — US disclosed
EP-0050458-A2 2-Guanidino-4-heteroarylthiazoles and pharmaceutical compositions containing them PFIZER INC. (US) 1982-04-28 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090139537-A1 HAIR RELAXING COMPOSITION COMPRISING AT LEAST ONE NON-HYDROXIDE IMINE KRT18, INMT, INHA CYP1A2 1788/4885CYP2C19 2598/4885SMN1; SMN2 3027/4885
US-20090194124-A1 Hair Shaping Kit and Process Comprising at Least One Non-Hydroxide Imine KRT18, KIT, PRDM7 CYP1A2 2280/4885CYP2C19 2140/4885SMN1; SMN2 3724/4885
US-20180265523-A1 ANTIBACTERIAL THERAPEUTICS AND PROPHYLACTICS CLPP, CFTR, ELANE CYP1A2 4552/4885CYP2C19 4070/4885SMN1; SMN2 3544/4885
US-20200140460-A1 ANTIBACTERIAL THERAPEUTICS AND PROPHYLACTICS CLPP, CFTR, ELANE CYP1A2 4552/4885CYP2C19 4070/4885SMN1; SMN2 3544/4885
US-10570152-B2 Antibacterial therapeutics and prophylactics CLPP, CFTR, ELANE CYP1A2 4552/4885CYP2C19 4070/4885SMN1; SMN2 3544/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.