Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.46 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.37 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.37 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piperidine SCHEMBL7617787 | 0.85 | MEN1 (0.36) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL12760818 | 0.83 | LMNA (0.46) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL385724 | 0.82 | LMNA (0.55) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL4896893 | 0.82 | LMNA (0.55) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL14354371 | 0.82 | ERN1 (0.53) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL3093687 | 0.80 | ERN1 (0.38) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL8972493 | 0.80 | ERN1 (0.38) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL28644100 | 0.80 | LMNA (0.52) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL640982 | 0.80 | ALDH1A1 (0.43) | LMNAKMT2AMEN1BLMALDH1A1 | |
| SCHEMBL12610848 | 0.78 | LMNA (0.50) | LMNAKMT2AMEN1THRBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114089599-A | Metal nanoparticle-based photoresist composition and application thereof | 中国科学院理化技术研究所 | 2022-02-25 | — | — | CN | claimed |
| EP-0635004-B1 | 4-DIPHENYLMETHYL PIPERIDINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | MERRELL PHARMA INC (US) | 2002-07-17 | — | — | EP | claimed |
| US-5675009-A | Process for piperidine derivatives | MERRELL PHARMACEUTICALS INC. (US) | 1997-10-07 | — | — | US | claimed |
| US-5663353-A | Process for piperidine derivatives | MERRELL PHARMACEUTICALS INC. (US) | 1997-09-02 | — | — | US | claimed |
| US-5654433-A | Process for piperidine derivatives | MERRELL PHARMACEUTICALS INC. (US) | 1997-08-05 | — | — | US | claimed |
| US-5652370-A | Process for piperidine derivatives | MERRELL PHARMACEUTICALS INC. (US) | 1997-07-29 | — | — | US | claimed |
| US-5650516-A | Process for piperidine derivatives | MERRELL PHARMACEUTICALS INC. (US) | 1997-07-22 | — | — | US | claimed |
| US-5644061-A | Process for piperidine derivatives | MERRELL PHARMACEUTICALS INC. (US) | 1997-07-01 | — | — | US | claimed |
| US-5618940-A | Process for piperidine derivatives | MERRELL PHARMACEUTICALS INC. (US) | 1997-04-08 | — | — | US | claimed |
| EP-0635004-A1 | 4-DIPHENYLMETHYL PIPERIDINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | MERRELL PHARMACEUTICALS INC. (US) | 1995-01-25 | — | — | EP | claimed |
| WO-1993021156-A1 | 4-DIPHENYLMETHYL PIPERIDINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-10-28 | — | — | WO | claimed |
| CN-114089599-A | Metal nanoparticle-based photoresist composition and application thereof | 中国科学院理化技术研究所 | 2022-02-25 | — | — | CN | disclosed |
| CN-106980228-B | Method for preparing durable micro-nano structure on curved glass | 鲁东大学 | 2020-07-10 | — | — | CN | disclosed |
| EP-2505576-B1 | CYCLIC COMPOUND, PROCESS FOR PRODUCTION THEREOF, RADIATION-SENSITIVE COMPOSITION, AND RESIST PATTERN FORMATION METHOD | MITSUBISHI GAS CHEMICAL CO (JP) | 2019-04-24 | — | — | EP | disclosed |
| US-20160137648-A1 | TETRAAZA-CYCLOPENTA[A]INDENYL DERIVATIVES | ASCENEURON SA (CH) | 2016-05-19 | — | — | US | disclosed |
| US-5644061-A | Process for piperidine derivatives | MERRELL PHARMACEUTICALS INC. (US) | 1997-07-01 | — | — | US | disclosed |
| US-5631375-A | Process for piperidine derivatives | MERRELL PHARMACEUTICALS, INC. (US) | 1997-05-20 | — | — | US | disclosed |
| US-5618940-A | Process for piperidine derivatives | MERRELL PHARMACEUTICALS INC. (US) | 1997-04-08 | — | — | US | disclosed |
| EP-0635004-A1 | 4-DIPHENYLMETHYL PIPERIDINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | MERRELL PHARMACEUTICALS INC. (US) | 1995-01-25 | — | — | EP | disclosed |
| WO-1993021156-A1 | 4-DIPHENYLMETHYL PIPERIDINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160137648-A1 | TETRAAZA-CYCLOPENTA[A]INDENYL DERIVATIVES | CHRM1, CHRM2, CHRM3 | LMNA 4307/4885KMT2A 2888/4885MEN1 2223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.