SCHEMBL4896893

SCHEMBL4896893

O=Cc1ccccc1C(O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.55
KMT2A Q03164 2/20 0.55
MEN1 O00255 1/20 0.55
THRB P10828 1/20 0.55
BLM P54132 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
TRIM24 O15164 2/20 0.50
TRIM33 Q9UPN9 2/20 0.50
ALDH1A1 P00352 3/20 0.44
TSHR P16473 1/20 0.44
ERN1 O75460 4/20 0.41
HPGD P15428 1/20 0.40
HTT P42858 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
CYP2A6 P11509 1/20 0.40
SRC P12931 1/20 0.39
GAA P10253 1/20 0.38
PTGDR2 Q9Y5Y4 1/20 0.37
TLR2 O60603 1/20 0.35
TLR1 Q15399 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13428746 0.82 LMNA (0.50) LMNAKMT2AMEN1THRBBLM
SCHEMBL4093324 0.82 LMNA (0.50) LMNAKMT2AMEN1THRBBLM
SCHEMBL1325378 0.80 LMNA (0.48) LMNAKMT2AMEN1THRBBLM
SCHEMBL9789839 0.79 LMNA (0.46) LMNAKMT2AMEN1THRBBLM
SCHEMBL15376731 0.79 LMNA (0.48) LMNAKMT2AMEN1THRBBLM
SCHEMBL11318960 0.79 LMNA (0.46) LMNAKMT2AMEN1THRBBLM
SCHEMBL12760818 0.79 LMNA (0.46) LMNAKMT2AMEN1THRBBLM
SCHEMBL2944385 0.78 ALDH1A1 (0.46) LMNAKMT2AMEN1THRBBLM
SCHEMBL11214027 0.77 LMNA (0.44) LMNAKMT2AMEN1THRBBLM
SCHEMBL400210 0.77 LMNA (0.44) LMNAKMT2AMEN1THRBBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0475605-B1 Phenolic resin and method for preparing same MITSUI TOATSU CHEMICALS (JP) 1996-01-03 EP claimed
EP-0164705-B1 PROCESS FOR MANUFACTURING PHTHALALDEHYDACETALS BASF Aktiengesellschaft (DE) 1987-09-02 EP claimed
WO-2021126973-A1 COMPOUNDS MODULATING PROTEIN RECRUITMENT AND/OR DEGRADATION ORIONIS BIOSCIENCES, INC. (US) 2021-06-24 WO disclosed
US-7402708-B2 Method for producing aqueous ortho-phthalaldehyde solutions DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) 2008-07-22 US disclosed
EP-1911830-A1 Process for the reduction of sulfur, nitrogen and the production of useful oxygenates from hydrocarbon materials via one-pot selective oxidation Kocat Inc. (KR) 2008-04-16 EP disclosed
US-20060199870-A1 acetal is converted into the o-phthalaldehyde by eliminating the corresponding alcohol; used in the sector of high-activity disinfection of endoscopes DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) 2006-09-07 US disclosed
US-7067288-B2 Nucleotide sequences which code for the mdhA gene DEGUSSA AG (DE) 2006-06-27 US disclosed
US-6995002-B2 Nucleotide sequences which code for the mdhA gene DEGUSSA AG (DE) 2006-02-07 US disclosed
EP-1297148-B1 NUCLEOTIDE SEQUENCES WHICH CODE FOR THE MDHA GENE FROM CORYNEBACTERIUM GLUTAMICUM DEGUSSA (DE) 2005-12-14 EP disclosed
US-6780883-B2 ANTICHOLESTEROL AGENTS; CARDIOVASCULAR DISORDERS; ANTILIPEMIC AGENTS; RESTENOSIS; DIETETICS WARNER-LAMBERT COMPANY 2004-08-24 US disclosed
US-20040142454-A1 Nucleotide sequences which code for the mdhA gene DEGUSSA AG (DE) 2004-07-22 US disclosed
EP-1297148-A1 NUCLEOTIDE SEQUENCES WHICH CODE FOR THE MDHA GENE FROM CORYNEBACTERIUM GLUTAMICUM Degussa AG (DE) 2003-04-02 EP disclosed
US-20020156281-A1 Amide inhibitors of microsomal triglyceride transfer protein BOOTH RICHARD JOHN (US) 2002-10-24 US disclosed
US-20020037568-A1 Nucleotide sequences which code for the mdhA gene DEGUSSA AG (DE) 2002-03-28 US disclosed
WO-2002002778-A1 NUCLEOTIDE SEQUENCES WHICH CODE FOR THE MDHA GENE FROM CORYNEBACTERIUM GLUTAMICUM DEGUSSA AG (DE) 2002-01-10 WO disclosed
US-5078838-A By electrochemical anodic oxidation of benzyl derivatives in the presence of an aliphatic alcohol BASF AKTIENGESELLSCHAFT (DE) 1992-01-07 US disclosed
US-4588482-A Preparation of phthalaldehyde acetals BASF AKTIENGESELLSCHAFT (DE) 1986-05-13 US disclosed
US-4588482-A Preparation of phthalaldehyde acetals BASF AKTIENGESELLSCHAFT (DE) 1986-05-13 US disclosed
US-4588482-A Preparation of phthalaldehyde acetals BASF AKTIENGESELLSCHAFT (DE) 1986-05-13 US disclosed
EP-0164705-A2 Process for manufacturing phthalaldehydacetals BASF Aktiengesellschaft (DE) 1985-12-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020156281-A1 Amide inhibitors of microsomal triglyceride transfer protein CETP, MTTP, LCAT LMNA 4203/4885KMT2A 1440/4885MEN1 4612/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.