Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | MLYCD | O95822 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18880072 | 0.87 | ALDH1A1 (0.73) | ALDH1A1KMT2AMAPTMEN1RXFP1 | |
| SCHEMBL14072820 | 0.85 | ALDH1A1 (0.56) | ALDH1A1KMT2AMAPTMEN1RXFP1 | |
| SCHEMBL12309897 | 0.85 | PGR (0.56) | ALDH1A1KMT2AMAPTMEN1RXFP1 | |
| SCHEMBL10191884 | 0.83 | ALDH1A1 (0.54) | ALDH1A1KMT2AMAPTMEN1RXFP1 | |
| SCHEMBL8691196 | 0.79 | ALDH1A1 (0.63) | ALDH1A1KMT2AMAPTMEN1RXFP1 | |
| SCHEMBL178429 | 0.79 | MAPT (0.71) | ALDH1A1KMT2AMAPTMEN1RXFP1 | |
| SCHEMBL13390897 | 0.79 | KMT2A (0.63) | ALDH1A1KMT2AMAPTMEN1RXFP1 | |
| SCHEMBL2608916 | 0.79 | MAPT (0.63) | ALDH1A1KMT2AMAPTMEN1RXFP1 | |
| SCHEMBL599684 | 0.79 | KMT2A (0.73) | ALDH1A1KMT2AMAPTMEN1RAB9A | |
| SCHEMBL7348164 | 0.78 | KMT2A (0.53) | ALDH1A1KMT2AMAPTMEN1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8445516-B2 | Pharmaceutical composition for promoting angiogenesis | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-05-21 | — | — | US | disclosed |
| US-20090187025-A1 | Pharmaceutical composition for promoting angiogenesis | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2009-07-23 | — | — | US | disclosed |
| CN-100473383-C | Pharmaceutical composition for promoting angiogenesis | OTSUKA PHARMA CO LTD (JP) | 2009-04-01 | — | — | CN | disclosed |
| EP-1708705-B1 | USE OF PIPERIDINE DERIVATIVES FOR PROMOTING ANGIOGENESIS | OTSUKA PHARMA CO LTD (JP) | 2009-02-18 | — | — | EP | disclosed |
| CN-1905877-A | Pharmaceutical composition for promoting angiogenesis | OTSUKA PHARMA CO LTD (JP) | 2007-01-31 | — | — | CN | disclosed |
| EP-1708705-A1 | PHARMACEUTICAL COMPOSITION FOR PROMOTING ANGIOGENESIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-10-11 | — | — | EP | disclosed |
| WO-2005072734-A1 | PHARMACEUTICAL COMPOSITION FOR PROMOTING ANGIOGENESIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-08-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090187025-A1 | Pharmaceutical composition for promoting angiogenesis | FLT1, FLT4, KDR | ALDH1A1 246/4885KMT2A 3216/4885MAPT 4708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.