Phosphonic Acid

Phosphonic Acid

SCHEMBL4093814

Cc1ccc(CCl)cc1C.O=[PH](O)O.O=[PH](O)O

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
CNR1 P21554 1/20 0.38
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
CCR2 P41597 1/20 0.36
POLB P06746 1/20 0.36
NR1H4 Q96RI1 1/20 0.36
NQO1 P15559 2/20 0.36
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
PRSS1 P07477 1/20 0.35
PRSS2 P07478 1/20 0.35
PRSS3 P35030 1/20 0.35
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
LMNA P02545 1/20 0.35
GAA P10253 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4093819 0.89 ALDH1A1 (0.38) ALDH1A1CNR1ESR1ESR2CCR2
SCHEMBL540384 0.87 ALDH1A1 (0.40) ALDH1A1CNR1ESR1ESR2CCR2
SCHEMBL29377856 0.87 ALDH1A1 (0.40) ALDH1A1CNR1ESR1ESR2CCR2
SCHEMBL19512351 0.85 ALDH1A1 (0.39) ALDH1A1CNR1ESR1ESR2CCR2
Phosphonic Acid SCHEMBL4098634 0.82 S1PR1 (0.41) ALDH1A1CNR1ESR1ESR2POLB
SCHEMBL16230317 0.72 TSHR (0.46) ALDH1A1CNR1ESR1ESR2POLB
SCHEMBL13707209 0.72 ESR1 (0.68) ALDH1A1ESR1ESR2CA1CA2
SCHEMBL30196675 0.72 ESR1 (0.68) ALDH1A1ESR1ESR2CA1CA2
SCHEMBL5972951 0.72 CYP3A4 (0.43) ESR1ESR2CCR2POLBNQO1
SCHEMBL4098636 0.72 S1PR1 (0.38) ALDH1A1ESR1ESR2POLBNR1H4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8293029-B2 Colored conversion layers on metal surfaces HENKEL AG & CO. KGAA (DE) 2012-10-23 US disclosed
US-20090214883-A1 CHROMIUM-FREE, THERMALLY CURABLE CORROSION PROTECTION COMPOSITION HENKEL AG & CO. KGAA (DE) 2009-08-27 US disclosed
US-20060173099-A1 Colored conversion layers on metal surfaces HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2006-08-03 US disclosed