Phosphonic Acid

Phosphonic Acid

SCHEMBL4098634

Cc1ccc(CO)cc1C.O=[PH](O)O.O=[PH](O)O

nearest known ligand 0.42

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 1/20 0.41
MEN1 O00255 1/20 0.39
LMNA P02545 1/20 0.39
GAA P10253 1/20 0.39
KMT2A Q03164 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
POLB P06746 1/20 0.37
HSD17B10 Q99714 1/20 0.37
NR1H4 Q96RI1 1/20 0.37
NQO1 P15559 2/20 0.36
PRSS1 P07477 1/20 0.36
PRSS2 P07478 1/20 0.36
PRSS3 P35030 1/20 0.36
CYP4F2 P78329 1/20 0.36
CYP4A11 Q02928 1/20 0.36
CNR1 P21554 1/20 0.36
S1PR4 O95977 1/20 0.35
CYP1A2 P05177 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL93048 0.89 S1PR1 (0.47) S1PR1MEN1LMNAGAAKMT2A
SCHEMBL4098636 0.89 S1PR1 (0.38) S1PR1MEN1LMNAGAAKMT2A
Phosphonic Acid SCHEMBL4093814 0.82 ALDH1A1 (0.38) MEN1LMNAGAAKMT2AL3MBTL1
SCHEMBL12710443 0.74 HSD17B10 (0.39) S1PR1ESR1ESR2POLBHSD17B10
SCHEMBL4134649 0.74 ESR1 (0.40) S1PR1ESR1ESR2HSD17B10PRSS1
SCHEMBL4056677 0.74 HSD17B10 (0.43) S1PR1ESR1ESR2HSD17B10PRSS1
SCHEMBL4919837 0.73 ESR2 (0.43) S1PR1ESR1ESR2HSD17B10CYP4F2
SCHEMBL148755 0.73 SHBG (0.48) S1PR1ESR1ESR2HSD17B10CYP4F2
SCHEMBL29741490 0.73 SHBG (0.48) S1PR1ESR1ESR2HSD17B10CYP4F2
SCHEMBL11967053 0.72 BACE1 (0.40) S1PR1HSD17B10CYP4F2CYP4A11SHBG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8293029-B2 Colored conversion layers on metal surfaces HENKEL AG & CO. KGAA (DE) 2012-10-23 US disclosed
US-20090214883-A1 CHROMIUM-FREE, THERMALLY CURABLE CORROSION PROTECTION COMPOSITION HENKEL AG & CO. KGAA (DE) 2009-08-27 US disclosed
US-20060173099-A1 Colored conversion layers on metal surfaces HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2006-08-03 US disclosed