SCHEMBL540384

SCHEMBL540384

Cc1ccc(CCl)cc1C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.40
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
LMNA P02545 3/20 0.37
HTT P42858 1/20 0.37
CNR1 P21554 1/20 0.37
MAPT P10636 3/20 0.36
KDM4E B2RXH2 2/20 0.36
GAA P10253 2/20 0.36
CYP3A4 P08684 3/20 0.36
CYP2C19 P33261 3/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
CYP1A2 P05177 2/20 0.36
CYP2D6 P10635 2/20 0.36
TTR P02766 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
CYP2C9 P11712 1/20 0.36
CCR2 P41597 1/20 0.35
NPBWR1 P48145 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29377856 1.00 ALDH1A1 (0.40) ALDH1A1ESR1ESR2LMNAHTT
SCHEMBL19512351 0.97 ALDH1A1 (0.39) ALDH1A1ESR1ESR2LMNAHTT
Phosphonic Acid SCHEMBL4093814 0.87 ALDH1A1 (0.38) ALDH1A1ESR1ESR2LMNACNR1
SCHEMBL5972951 0.82 CYP3A4 (0.43) ESR1ESR2LMNAHTTGAA
SCHEMBL5492827 0.82 ESR1 (0.38) ESR1ESR2LMNAKDM4ECYP3A4
SCHEMBL4093819 0.81 ALDH1A1 (0.38) ALDH1A1ESR1ESR2LMNAHTT
SCHEMBL6914100 0.80 ESR1 (0.37) ESR1ESR2KDM4ECYP3A4CYP2C19
SCHEMBL5598364 0.80 PON1 (0.37) ESR1ESR2KDM4ECYP3A4CYP2C19
SCHEMBL11862455 0.80 CNR1 (0.41) ALDH1A1ESR1ESR2LMNAHTT
SCHEMBL1291043 0.80 TTR (0.40) ESR1ESR2KDM4ECYP3A4CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 443 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120158258-A Double-component pouring type high-temperature-resistant high-toughness polyurethane structural adhesive and preparation method thereof 四川东树新材料有限公司 2025-06-17 CN claimed
CN-120005504-A Heavy anti-corrosion coating with corrosion inhibition and self-healing synergistic effect and preparation method thereof 自然资源部天津海水淡化与综合利用研究所 2025-05-16 CN claimed
CN-119931483-A Single-component self-healing polyurethane heavy-duty anticorrosive coating and preparation method thereof 自然资源部天津海水淡化与综合利用研究所 2025-05-06 CN claimed
CN-116162221-B Polyurethane sealing material and preparation method thereof 中国科学院长春应用化学研究所 2024-12-17 CN claimed
CN-118894673-A Preparation method of rapid repair inorganic cementing material 海南津桓建材科技有限公司 2024-11-05 CN claimed
CN-116836361-B Polyurethane resin suitable for dry gold stamping and preparation method thereof 浙江禾欣科技有限公司 2024-08-13 CN claimed
CN-115892736-B Biodegradable paper-plastic composite film and preparation method and application thereof 山东联欣环保科技有限公司 2024-08-09 CN claimed
CN-117887342-A Anticorrosive paint and preparation method thereof 安徽泽众安全科技有限公司 2024-04-16 CN claimed
CN-117777411-A Crosslinked methylene aromatic hydrocarbon high polymer and synthesis method thereof 乐山师范学院 2024-03-29 CN claimed
CN-117567976-A Rapid-curing high-toughness low-shrinkage polyurethane structural adhesive and preparation method thereof 四川东树新材料有限公司 2024-02-20 CN claimed
CN-112708098-B Wet-process polyurethane resin and preparation method and application thereof 上海汇得科技股份有限公司 2022-07-19 CN claimed
CN-114736350-A Preparation method of dimer addition product of aliphatic diisocyanate 安徽科瑞达新材料有限公司 2022-07-12 CN claimed
CN-114621412-A Flame-retardant antibacterial thermoplastic polyurethane elastomer and preparation method thereof 万华化学集团股份有限公司 2022-06-14 CN claimed
CN-106398080-B A kind of ammonium cross-linking type block copolymer/graphene composite material and preparation method thereof 北京化工大学 2018-12-04 CN claimed
CN-106398080-A Aminated cross-linked segmented copolymer/graphene composite material and preparation method thereof 北京化工大学 2017-02-15 CN claimed
EP-0970079-A1 FARNESYL TRANSFERASE INHIBITING 1,8-ANNELATED QUINOLINONE DERIVATIVES SUBSTITUTED WITH N- OR C-LINKED IMIDAZOLES JANSSEN PHARMACEUTICA N.V. (BE) 2000-01-12 EP claimed
WO-1998040383-A1 FARNESYL TRANSFERASE INHIBITING 1,8-ANNELATED QUINOLINONE DERIVATIVES SUBSTITUTED WITH N- OR C-LINKED IMIDAZOLES JANSSEN PHARMACEUTICA N.V. (BE) 1998-09-17 WO claimed
US-4209653-A α-Olefin dimer isomerization using organo-halogens SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1980-06-24 US claimed
US-3993690-A Method of obtaining aromatic tri-or-tetracarboxylic acids SUVOROV BORIS VIKTOROVICH 1976-11-23 US claimed
US-3962357-A FROM SUBSTITUTED ETHYLTOLUENE, CONTINUOUS, SINGLE STEP ROHM AND HAAS COMPANY (US) 1976-06-08 US claimed