SCHEMBL4094158

SCHEMBL4094158

COP1(=O)Oc2ccccc2O1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RX4 Q99571 1/20 0.34
ACHE P22303 3/20 0.33
HPGD P15428 3/20 0.32
CA4 P22748 2/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
CA14 Q9ULX7 1/20 0.32
ALDH1A1 P00352 2/20 0.31
TP53 P04637 2/20 0.31
POLB P06746 2/20 0.31
MAPT P10636 2/20 0.31
ALOX15 P16050 2/20 0.31
KDM4E B2RXH2 1/20 0.31
MAP2K7 O14733 1/20 0.31
GMNN O75496 1/20 0.31
LMNA P02545 1/20 0.31
CYP1A2 P05177 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19912658 0.86 MAOA (0.47) ACHEHPGDALDH1A1KDM4ECYP1A2
SCHEMBL10492363 0.85 CYP1A2 (0.38) HPGDALDH1A1TP53POLBMAPT
SCHEMBL9125469 0.80
SCHEMBL9124669 0.79 ABCG2 (0.33) HPGDABCG2ITGB2ICAM1ITGAL
SCHEMBL9122176 0.79 MAPT (0.35) ACHEHPGDCA12CA9ALDH1A1
SCHEMBL10492375 0.79 CA1 (0.36) HPGDCA12CA1CA2CA7
SCHEMBL9124534 0.79 AHR (0.39)
SCHEMBL12875556 0.79 BCHE (0.42) ACHEHPGDCA12CA1CA2
SCHEMBL11509206 0.79 BCHE (0.42) ACHEHPGDCA12CA1CA2
SCHEMBL9122194 0.78 PDE4B (0.36) ACHECA4ALDH1A1TP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2547822-B1 PROCESS FOR FIBRILLATING LIGNOCELLULOSIC MATERIAL, FIBRES AND THEIR USE UNIV HELSINKI (FI) 2014-07-02 EP disclosed
US-8198434-B2 Process for preparing cefsulodin sodium IDEXX LABORATORIES, INC. (US) 2012-06-12 US disclosed
US-8198434-B2 Process for preparing cefsulodin sodium IDEXX LABORATORIES, INC. (US) 2012-06-12 US disclosed
US-20100113768-A1 PROCESS FOR PREPARING CEFSULODIN SODIUM IDEXX LABORATORIES, INC. (US) 2010-05-06 US disclosed
US-20100113768-A1 PROCESS FOR PREPARING CEFSULODIN SODIUM IDEXX LABORATORIES, INC. (US) 2010-05-06 US disclosed
US-7622487-B2 Piperidine derivative, process for producing the same, and use TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-11-24 US disclosed
US-20090186874-A1 Carboxamide derivative and use thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-07-23 US disclosed
US-7439289-B2 Benzoylresorcinol-based phosphate ester compounds as flame retardants INDSPEC CHEMICAL CORPORATION (US) 2008-10-21 US disclosed
US-7439289-B2 Benzoylresorcinol-based phosphate ester compounds as flame retardants INDSPEC CHEMICAL CORPORATION (US) 2008-10-21 US disclosed
US-7365113-B2 Phosphate ester flame retardants from resorcinol-ketone reaction products INDSPEC CHEMICAL CORPORATION 2008-04-29 US disclosed
EP-0216385-A2 Antibacterial compounds Takeda Chemical Industries, Ltd. (JP) 1987-04-01 EP disclosed
US-4642365-A REACTING A PYROCATECHOL DERIVATIVE AND DIHALOPHOSPHOROUS COMPOUND TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1987-02-10 US disclosed
EP-0203271-A2 Antibacterial compounds, their production and use Takeda Chemical Industries, Ltd. (JP) 1986-12-03 EP disclosed
WO-1986005183-A1 ANTIBACTERIAL COMPOUNDS, THEIR PRODUCTION AND USE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1986-09-12 WO disclosed
EP-0164113-A2 3-pyrazolo(1,5-a)pyridinium cephem compounds, their production and use Takeda Chemical Industries, Ltd. (JP) 1985-12-11 EP disclosed
EP-0164122-A2 Cephem compounds Takeda Chemical Industries, Ltd. (JP) 1985-12-11 EP disclosed
EP-0160969-A2 Cephem compounds Takeda Chemical Industries, Ltd. (JP) 1985-11-13 EP disclosed
EP-0160252-A2 Antibacterial compounds Takeda Chemical Industries, Ltd. (JP) 1985-11-06 EP disclosed
EP-0135683-A1 Method for production of cephalosporin compounds Takeda Chemical Industries, Ltd. (JP) 1985-04-03 EP disclosed
EP-0074611-A2 Method for production of cephalosporin compounds Takeda Chemical Industries, Ltd. (JP) 1983-03-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090186874-A1 Carboxamide derivative and use thereof NTSR2, NTSR1, CNR2 P2RX4 587/4885ACHE 898/4885HPGD 600/4885
US-20100113768-A1 PROCESS FOR PREPARING CEFSULODIN SODIUM PEF1, PCSK9, SLC6A5 P2RX4 4019/4885ACHE 2520/4885HPGD 576/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.