SCHEMBL4094661

SCHEMBL4094661

O=P(O)(O)C(c1ccccc1)P(=O)(O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 1.00
ACP3 P15309 13/20 0.54
PGK1 P00558 3/20 0.48
PGK2 P07205 3/20 0.48
CA12 O43570 1/20 0.46
CA9 Q16790 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9301497 0.86 SRC (0.75) SRCACP3PGK1PGK2CA12
SCHEMBL9450680 0.82 SRC (0.70) SRCACP3PGK1PGK2
SCHEMBL31107106 0.81 SRC (0.67) SRCACP3
SCHEMBL3385301 0.81 SRC (0.67) SRCACP3
SCHEMBL8855634 0.81 SRC (0.67) SRCACP3PGK1PGK2CA12
SCHEMBL27465781 0.80 SRC (0.64) SRCACP3PGK1PGK2
SCHEMBL2171583 0.79 SRC (0.65) SRCACP3PGK1PGK2
SCHEMBL232244 0.79 ACP3 (0.79) SRCACP3PGK1PGK2
Hydrochloric Acid SCHEMBL1133241 0.77 ACP3 (0.76) SRCACP3
Alpha Hydroxy Benzylphosphonate SCHEMBL5744616 0.77 PGK1 (0.71) SRCACP3PGK1PGK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0857227-B1 SHORT DURATION HOT SEAL FOR ANODISED METAL SURFACES HENKEL KGAA (DE) 2000-01-26 EP claimed
EP-4662319-A2 PERSONALIZED CRISPR PROFILING FOR CANCER Integrate Bioscience LLC (US) 2025-12-17 EP disclosed
WO-2024168301-A2 PERSONALIZED CRISPR PROFILING FOR CANCER FUNCTION ONCOLOGY, INC. (US) 2024-08-15 WO disclosed
EP-3348269-B1 MEVALONATE PATHWAY INHIBITOR AS HIGHLY-EFFECTIVE VACCINE ADJUVANT UNIV TSINGHUA (CN) 2023-11-15 EP disclosed
EP-3681504-B1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ICAGEN INC (US) 2023-08-23 EP disclosed
US-11573224-B2 Methods of detection using X-ray fluorescence ICAGEN, LLC (US) 2023-02-07 US disclosed
US-20220387584-A1 MEVALONATE PATHWAY INHIBITOR AS HIGHLY-EFFICIENT VACCINE ADJUVANT TSINGHUA UNIVERSITY (CN) 2022-12-08 US disclosed
US-11446398-B2 Regulated biocircuit systems OBSIDIAN THERAPEUTICS, INC. (US) 2022-09-20 US disclosed
US-11382971-B2 Mevalonate pathway inhibitor as highly-efficient vaccine adjuvant TSINGHUA UNIVERSITY (CN) 2022-07-12 US disclosed
US-20190321465-A1 MEVALONATE PATHWAY INHIBITOR AS HIGHLY-EFFICIENT VACCINE ADJUVANT TSINGHUA UNIVERSITY (CN) 2019-10-24 US disclosed
US-5156824-A Extracting metals especially uranium, actinides and lanthanides COMPAGNIE FRANCAISE DE MOKTA (FR) 1992-10-20 US disclosed
US-4774262-A CROSSLINKED, BINDING, ESTERIFICATION RECOVERING METALS MINEMET RECHERCHE (FR) 1988-09-27 US disclosed
EP-0210571-A1 Phosphonopyridines and their 1,4-dihydroderivatives BOEHRINGER BIOCHEMIA ROBIN S.p.A. (IT) 1987-02-04 EP disclosed
US-4579720-A USING HYDROXYMETHANE DIPHOSPHONIC ACID PLAINS CHEMICAL DEVELOPMENT CO. (US) 1986-04-01 US disclosed
US-4440646-A HYDROXY OR HALOALKANEPHOSPHONATES PLAINS CHEMICAL DEVELOPMENT CO. (US) 1984-04-03 US disclosed
EP-0015370-B1 DIPHOSPHONATE OR PHOSPHATE-PHOSPHONATE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM SYMPHAR S.A. (CH) 1983-01-12 EP disclosed
US-4188234-A STABILIZATION OF VINYL POLYMERS, POLYPHOSPHONIC ACID CHELATING AGENT, PROTECTIVE COATINGS PLAINS CHEMICAL DEVELOPMENT CO. (US) 1980-02-12 US disclosed
US-4150024-A Reaction products of epsilon-caprolactam with vicinal hydroxyalkylamines and alkoxylation products thereof HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1979-04-17 US disclosed
US-4116990-A OF NON-ALKALI METAL IONS WITH PHOSPHORUS CHELATING COMPOUND PLAINS CHEMICAL DEVELOPMENT CO. (US) 1978-09-26 US disclosed
US-4020091-A TIN SALTS OF POLYPHOSPHONIC ACIDS PLAINS CHEMICAL DEVELOPMENT CO. (US) 1977-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190321465-A1 MEVALONATE PATHWAY INHIBITOR AS HIGHLY-EFFICIENT VACCINE ADJUVANT GGPS1, HMGCR, COASY SRC 1894/4885ACP3 662/4885PGK1 78/4885
US-11382971-B2 Mevalonate pathway inhibitor as highly-efficient vaccine adjuvant GGPS1, HMGCR, COASY SRC 1894/4885ACP3 677/4885PGK1 74/4885
US-20220387584-A1 MEVALONATE PATHWAY INHIBITOR AS HIGHLY-EFFICIENT VACCINE ADJUVANT COASY, GGPS1, HMGCR SRC 1887/4885ACP3 668/4885PGK1 80/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.