Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TK1 | P04183 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3412829 | 0.83 | KMT2A (0.48) | TYMPTK1 | |
| SCHEMBL4094686 | 0.81 | TYMP (0.63) | TYMPMAPK1HPGD | |
| SCHEMBL3415213 | 0.81 | DPYD (0.34) | TYMP | |
| SCHEMBL3406750 | 0.80 | KMT2A (0.34) | TYMP | |
| SCHEMBL10474817 | 0.79 | TYMP (0.56) | TYMPMAPK1TK1HPGD | |
| SCHEMBL12748529 | 0.79 | TYMP (0.51) | TYMPMAPK1TK1HPGD | |
| SCHEMBL15498801 | 0.79 | TYMP (0.51) | TYMPMAPK1TK1HPGD | |
| SCHEMBL12859844 | 0.78 | TYMP (0.53) | TYMPMAPK1TK1HPGD | |
| SCHEMBL10474814 | 0.78 | TYMP (0.56) | TYMPMAPK1TK1HPGD | |
| SCHEMBL10474924 | 0.77 | TYMP (0.59) | TYMPMAPK1TK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203636-A1 | Prevention and Treatment of Cancer and Other Diseases | ALT SOLUTIONS, INC. | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203636-A1 | Prevention and Treatment of Cancer and Other Diseases | TERT, POLRMT, RNASE1 | TYMP 6/4885MAPK1 3751/4885TK1 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.