Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | NPC1 | O15118 | 1/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.70 |
| ▸ | USP1 | O94782 | 8/20 | 0.67 |
| ▸ | WDR48 | Q8TAF3 | 8/20 | 0.67 |
| ▸ | APP | P05067 | 1/20 | 0.64 |
| ▸ | PDE5A | O76074 | 3/20 | 0.63 |
| ▸ | GBA1 | P04062 | 1/20 | 0.63 |
| ▸ | ATM | Q13315 | 1/20 | 0.63 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.61 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.61 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.57 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4868136 | 0.92 | MEN1 (0.76) | MEN1KMT2ALMNAMAPTUSP1 | |
| SCHEMBL4084636 | 0.89 | MEN1 (0.65) | MEN1KMT2ALMNAMAPTKDM4E | |
| SCHEMBL4085140 | 0.82 | ABCG2 (0.83) | MEN1KMT2ALMNAMAPTKDM4E | |
| SCHEMBL3641849 | 0.79 | RAD52 (0.76) | KMT2ALMNAMAPTKDM4ENPSR1 | |
| SCHEMBL4864021 | 0.79 | APP (0.73) | MEN1KMT2ALMNAMAPTKDM4E | |
| SCHEMBL2583554 | 0.79 | MEN1 (1.00) | MEN1KMT2ALMNAMAPTUSP1 | |
| SCHEMBL4848730 | 0.79 | ABCG2 (0.69) | MEN1KMT2ALMNAMAPTKDM4E | |
| SCHEMBL1084183 | 0.79 | MEN1 (0.89) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL27899411 | 0.79 | MEN1 (0.83) | MEN1KMT2ALMNAMAPTKDM4E | |
| SCHEMBL1083763 | 0.79 | PDE5A (1.00) | MEN1KMT2ALMNAMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090209536-A1 | AMINOQUINAZOLINE CANNABINOID RECEPTOR MODULATORS FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209536-A1 | AMINOQUINAZOLINE CANNABINOID RECEPTOR MODULATORS FOR TREATMENT OF DISEASE | CNR2, CNR1, GPR18 | MEN1 718/4885KMT2A 1424/4885LMNA 2728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.