Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 12/20 | 0.68 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.68 |
| ▸ | KDM1A | O60341 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 8/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.64 |
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | HBB | P68871 | 1/20 | 0.64 |
| ▸ | SYK | P43405 | 1/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4085140 | 0.82 | ABCG2 (0.83) | ABCG2KDM1ATP53KDM4ELMNA | |
| SCHEMBL4094753 | 0.79 | MEN1 (0.70) | ABCG2CYP1A2KDM1ACYP3A4CYP2D6 | |
| SCHEMBL4868136 | 0.79 | MEN1 (0.76) | ABCG2CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL16404336 | 0.78 | SYK (1.00) | ABCG2CYP1A2CYP1A1KDM1ACYP3A4 | |
| SCHEMBL1084176 | 0.78 | CYP2D6 (0.68) | ABCG2CYP1A2KDM1ACYP3A4CYP2D6 | |
| SCHEMBL26911304 | 0.78 | CHEK1 (0.59) | ABCG2CYP1A2KDM1ACYP3A4CYP2D6 | |
| SCHEMBL28147423 | 0.78 | MEN1 (0.65) | ABCG2KDM1AMEN1KMT2A | |
| SCHEMBL14529187 | 0.77 | CYP1A2 (1.00) | CYP1A2CYP3A4CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL14727634 | 0.76 | CYP1A2 (0.61) | ABCG2CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL16038183 | 0.75 | ABCG2 (0.56) | ABCG2KDM1ACYP3A4CYP2D6TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7390907-B2 | Vanilloid receptor ligands and their use in treatments | AMGEN INC. (US) | 2008-06-24 | — | — | US | disclosed |
| EP-1670794-A2 | VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS | Amgen Inc. (US) | 2006-06-21 | — | — | EP | disclosed |
| US-20050153984-A1 | Vanilloid receptor ligands and their use in treatments | AMGEN INC. | 2005-07-14 | — | — | US | disclosed |
| WO-2005033105-A2 | VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS | AMGEN INC. (US) | 2005-04-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050153984-A1 | Vanilloid receptor ligands and their use in treatments | TRPV1, TRPV2, TRPV3 | ABCG2 836/4885CYP1A2 2081/4885CYP1A1 2180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.