Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.56 |
| ▸ | AHR | P35869 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29826933 | 1.00 | MAOB (0.56) | MAOBAHRCYP3A4NPC1RAB9A | |
| SCHEMBL3072209 | 0.85 | MAOB (0.56) | MAOBAHRNPC1RAB9AKMT2A | |
| Propionic Acid SCHEMBL9056617 | 0.82 | ALDH1A1 (0.51) | MAOBCYP3A4NPC1RAB9AKMT2A | |
| SCHEMBL14501847 | 0.79 | LMNA (0.59) | MAOBAHRNPC1RAB9AKMT2A | |
| SCHEMBL6714496 | 0.79 | MAOB (0.43) | MAOBAHRCYP3A4NPC1RAB9A | |
| SCHEMBL11432359 | 0.78 | MAP2K4 (0.46) | MAOBAHRNPC1RAB9AMAP2K4 | |
| SCHEMBL13561062 | 0.78 | CYP19A1 (0.69) | MAOBCYP3A4NPC1RAB9AKMT2A | |
| SCHEMBL14919902 | 0.76 | AR (0.51) | CYP3A4NPC1RAB9AMAP2K4KMT2A | |
| SCHEMBL6966149 | 0.76 | MAOB (0.55) | MAOBNPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL11396839 | 0.75 | CYP3A4 (0.54) | MAOBCYP3A4NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12594261-B2 | Use of heterocyclic derivatives with cardiomyocyte proliferation activity for treatment of heart diseases | SHANGHAI EAST HOSPITAL (EAST HOSPITAL, TONGJI UNIVERSITY SCHOOL OF MEDICINE) (CN) | 2026-04-07 | — | — | US | claimed |
| CN-116589442-A | Preparation method of sesamol | 济南鸿湾生物技术有限公司 | 2023-08-15 | — | — | CN | claimed |
| CN-103275072-B | The preparation method of saracatinib | SUZHOU MINGYUE MEDICAL TECHNOLOGY CO., LTD. (CN) | 2016-01-20 | — | — | CN | claimed |
| CN-103275072-A | Preparation method of saracatinib | SUZHOU MINGYUE MEDICAL TECHNOLOGY CO LTD | 2013-09-04 | — | — | CN | claimed |
| CN-101243030-B | Method for producing 4-halocatechol compound | UBE INDUSTRIES, LTD. (JP) | 2012-02-01 | — | — | CN | claimed |
| EP-2029614-A2 | COLD MENTHOL RECEPTOR-1 ANTAGONISTS | Janssen Pharmaceutica, N.V. (BE) | 2009-03-04 | — | — | EP | claimed |
| CN-101243030-A | Method for producing 4-halocatechol compound | UBE INDUSTRIES (JP) | 2008-08-13 | — | — | CN | claimed |
| WO-2007134107-A2 | COLD MENTHOL RECEPTOR-1 ANTAGONISTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-11-22 | — | — | WO | claimed |
| US-12492193-B2 | Pyrazole derivatives for the treatment of cystic fibrosis | FONDAZIONE INSTITUTO ITALIANO DI TECNOLOGIA (IT) | 2025-12-09 | — | — | US | disclosed |
| CN-118891065-A | Anticancer therapy using radioactive PARP inhibitors | 癌症研究技术有限公司 | 2024-11-01 | — | — | CN | disclosed |
| CN-116589442-A | Preparation method of sesamol | 济南鸿湾生物技术有限公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-116589442-A | Preparation method of sesamol | 济南鸿湾生物技术有限公司 | 2023-08-15 | — | — | CN | disclosed |
| US-20230212157-A1 | PYRAZOLE DERIVATIVES FOR THE TREATMENT OF CYSTIC FIBROSIS | ISTITUTO GIANNINA GASLINI (IT) | 2023-07-06 | — | — | US | disclosed |
| US-11639355-B2 | Substituted pyrrolo[3,4-d]imidazoles as MDM2-p53 inhibitors | Luoxin Pharmaceutical (Shanghai) Co., Ltd. (CN) | 2023-05-02 | — | — | US | disclosed |
| US-5716954-A | ANTIINFLAMMATORY AGENT, ANTIHISTAMINES, IMMUNOSUPPRESSION,AUTOIMMUNE DISEASES | SYNTEX U.S.A. INC. (US) | 1998-02-10 | — | — | US | disclosed |
| CN-1143644-A | N-[(1,4-diazadicyclo [2,2,2] oct -2-yl methyl] benzoic amide derivatives, its preparing process and medicinal use | SYNTHELABO (FR) | 1997-02-26 | — | — | CN | disclosed |
| EP-0612321-A1 | PYRIDO PYRIDAZINONE AND PYRIDAZINTHIONE COMPOUNDS WITH PDE IV INHIBITING ACTIVITY | SYNTEX (U.S.A.) INC. (US) | 1994-08-31 | — | — | EP | disclosed |
| WO-1993007146-A1 | BENZO AND PYRIDO PYRIDAZINONE AND PYRIDAZINTHIONE COMPOUNDS WITH PDE IV INHIBITING ACTIVITY | SYNTEX (U.S.A.) INC. (US) | 1993-04-15 | — | — | WO | disclosed |
| US-4058607-A | DIHALOVINYL DIALKYL PHOSPHATE, 1,3-BENZODIOXOLES | AIRWICK INDUSTRIES, INC. (US) | 1977-11-15 | — | — | US | disclosed |
| US-3962415-A | Insecticide evaporator comprising DDVP with synergized benzodioxole compound as stabilizer | AIRWICK INDUSTRIES, INC. (US) | 1976-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212157-A1 | PYRAZOLE DERIVATIVES FOR THE TREATMENT OF CYSTIC FIBROSIS | CFTR, ABCC5, ABCC1 | MAOB 3977/4885AHR 804/4885CYP3A4 187/4885 |
| US-11639355-B2 | Substituted pyrrolo[3,4-d]imidazoles as MDM2-p53 inhibitors | TP53, MDM2, TP53BP1 | MAOB 3562/4885AHR 1570/4885CYP3A4 802/4885 |
| US-12492193-B2 | Pyrazole derivatives for the treatment of cystic fibrosis | CFTR, ABCC5, ABCC1 | MAOB 3977/4885AHR 804/4885CYP3A4 187/4885 |
| US-12594261-B2 | Use of heterocyclic derivatives with cardiomyocyte proliferation activity for treatment of heart diseases | TNNT2, TNNI3, CCNO | MAOB 351/4885AHR 489/4885CYP3A4 2048/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.