Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.43 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.43 |
| ▸ | GRM8 | O00222 | 3/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.40 |
| ▸ | GRM6 | O15303 | 2/20 | 0.40 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.40 |
| ▸ | KYNU | Q16719 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 6/20 | 0.38 |
| ▸ | CTSB | P07858 | 5/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4097234 | 0.88 | GSTP1 (0.45) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL4094926 | 0.86 | CTSL (0.44) | ALDH1A1GSTP1GSTM2KYNUCTSL | |
| SCHEMBL4096707 | 0.85 | GSTP1 (0.44) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL4088783 | 0.85 | GSTP1 (0.44) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL4089300 | 0.84 | GSTP1 (0.46) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL4084378 | 0.83 | CTSL (0.48) | ALDH1A1GSTP1GSTM2KYNUCTSL | |
| SCHEMBL4100004 | 0.83 | GSTP1 (0.48) | ALDH1A1GSTP1GSTM2KYNUCTSL | |
| SCHEMBL4089580 | 0.82 | GSTP1 (0.45) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL10000467 | 0.82 | GRM8 (0.61) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL4084706 | 0.81 | GSTP1 (0.45) | ALDH1A1GSTP1GSTM2KYNUCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090170813-A1 | Hypophosphorous Acid Derivatives and their Therapeutical Applications | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2009-07-02 | — | — | US | disclosed |
| EP-1937699-A2 | HYPOPHOSPHOROUS ACID DERIVATIVES AND THEIR THERAPEUTICAL APPLICATIONS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007052169-A2 | HYPOPHOSPHOROUS ACID DERIVATIVES AND THEIR THERAPEUTICAL APPLICATIONS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2007-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170813-A1 | Hypophosphorous Acid Derivatives and their Therapeutical Applications | P4HA1, CYP2R1, EGLN3 | ALDH1A1 2089/4885MEN1 1312/4885KMT2A 4135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.