Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 5/20 | 0.60 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | PDE5A | O76074 | 6/20 | 0.55 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.51 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.51 |
| ▸ | PRKACA | P17612 | 1/20 | 0.51 |
| ▸ | LTK | P29376 | 1/20 | 0.51 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.51 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.51 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.51 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.51 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.51 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3970144 | 0.83 | NPY5R (0.60) | NPY5RABCG2MEN1KMT2APDE5A | |
| SCHEMBL2255119 | 0.83 | NPY5R (0.60) | NPY5RABCG2MEN1KMT2APDE5A | |
| SCHEMBL4095242 | 0.82 | NPY5R (0.58) | NPY5RABCG2MEN1KMT2APDE5A | |
| SCHEMBL2256529 | 0.80 | NPY5R (0.55) | NPY5RABCG2MEN1KMT2APDE5A | |
| SCHEMBL4093298 | 0.78 | APP (0.65) | MEN1KMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL4969317 | 0.77 | NPY5R (0.66) | NPY5RABCG2MEN1KMT2APDE5A | |
| Acetonitrile SCHEMBL28943325 | 0.77 | NPY5R (0.53) | NPY5RABCG2MEN1KMT2APDE5A | |
| Hydrochloric Acid SCHEMBL8892043 | 0.76 | NPY5R (0.72) | NPY5RPOLBSMN1; SMN2SLC2A1ALOX15 | |
| SCHEMBL2591063 | 0.75 | NPY5R (1.00) | NPY5RABCG2MEN1KMT2APDE5A | |
| SCHEMBL10135256 | 0.74 | NPY5R (0.67) | NPY5RABCG2MEN1KMT2APDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090209536-A1 | AMINOQUINAZOLINE CANNABINOID RECEPTOR MODULATORS FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209536-A1 | AMINOQUINAZOLINE CANNABINOID RECEPTOR MODULATORS FOR TREATMENT OF DISEASE | CNR2, CNR1, GPR18 | NPY5R 201/4885ABCG2 3127/4885MEN1 718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.