Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.63 |
| ▸ | CLK4 | Q9HAZ1 | 6/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | METAP1 | P53582 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | JAK2 | O60674 | 1/20 | 0.59 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | USP2 | O75604 | 4/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1084100 | 0.86 | GBA1 (0.64) | GBA1MAPK1ALDH1A1KMT2AMETAP1 | |
| SCHEMBL1083993 | 0.86 | GBA1 (0.64) | GBA1MAPK1ALDH1A1KMT2AMETAP1 | |
| SCHEMBL1064493 | 0.84 | GBA1 (0.82) | GBA1MAPK1ALDH1A1KMT2AMETAP1 | |
| SCHEMBL17799807 | 0.83 | APP (0.68) | GBA1CYP1A2ALDH1A1KMT2AMETAP1 | |
| SCHEMBL22201478 | 0.81 | GBA1 (0.77) | GBA1MAPK1ALDH1A1KMT2AMETAP1 | |
| SCHEMBL13300259 | 0.80 | CYP1A2 (0.71) | GBA1CYP1A2CYP3A4CYP2C19CLK4 | |
| SCHEMBL18354431 | 0.78 | GBA1 (1.00) | GBA1CYP1A2CYP3A4CYP2C19CLK4 | |
| SCHEMBL13984093 | 0.78 | CYP1A2 (0.72) | GBA1CYP1A2CYP3A4CYP2C19CLK4 | |
| SCHEMBL4085082 | 0.77 | CYP1A2 (0.70) | GBA1CYP1A2CYP3A4CYP2C19CLK4 | |
| SCHEMBL1083779 | 0.76 | CYP1A2 (0.80) | GBA1CYP1A2CYP3A4CYP2C19CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090209536-A1 | AMINOQUINAZOLINE CANNABINOID RECEPTOR MODULATORS FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-08-20 | — | — | US | disclosed |
| US-20090209536-A1 | AMINOQUINAZOLINE CANNABINOID RECEPTOR MODULATORS FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-08-20 | — | — | US | disclosed |
| US-20090209536-A1 | AMINOQUINAZOLINE CANNABINOID RECEPTOR MODULATORS FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-08-20 | — | — | US | disclosed |
| WO-2008157500-A1 | AMINOQUINAZOLINE CANNABINOID RECEPTOR MODULATORS FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2008-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209536-A1 | AMINOQUINAZOLINE CANNABINOID RECEPTOR MODULATORS FOR TREATMENT OF DISEASE | CNR2, CNR1, GPR18 | GBA1 2059/4885CYP1A2 2477/4885CYP3A4 2113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.