Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6052746 | 1.00 | TACR1 (0.44) | TACR1CYP2C19SMN1; SMN2GAALMNA | |
| SCHEMBL4086816 | 1.00 | TACR1 (0.44) | TACR1CYP2C19SMN1; SMN2GAALMNA | |
| SCHEMBL3137156 | 0.87 | GBA1 (0.37) | SMN1; SMN2DPP4GBA1SLC18A3DPP8 | |
| SCHEMBL3129734 | 0.87 | GBA1 (0.37) | SMN1; SMN2DPP4GBA1SLC18A3DPP8 | |
| SCHEMBL3094922 | 0.86 | TACR1 (0.38) | TACR1CYP2C19SMN1; SMN2GAADPP4 | |
| SCHEMBL6704820 | 0.86 | TACR1 (0.38) | TACR1CYP2C19SMN1; SMN2GAADPP4 | |
| SCHEMBL6165781 | 0.82 | DPP4 (0.40) | TACR1CYP2C19SMN1; SMN2DPP4DPP8 | |
| SCHEMBL6052774 | 0.82 | FUCA1 (0.40) | TACR1CYP2C19SMN1; SMN2GAAGBA1 | |
| SCHEMBL6052771 | 0.82 | FUCA1 (0.40) | TACR1CYP2C19SMN1; SMN2GAAGBA1 | |
| SCHEMBL6052770 | 0.82 | FUCA1 (0.40) | TACR1CYP2C19SMN1; SMN2GAAGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090023703-A1 | Pyrrolopyridine-2-carboxylic acid amide inhibitors of glycogen phosphorylase | PROSIDION LIMITED (GB) | 2009-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023703-A1 | Pyrrolopyridine-2-carboxylic acid amide inhibitors of glycogen phosphorylase | PYGL, PYGM, PYGB | TACR1 3420/4885CYP2C19 905/4885SMN1; SMN2 3554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.