Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.43 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.40 |
| ▸ | PTGES | O14684 | 2/20 | 0.38 |
| ▸ | FABP1 | P07148 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | EDNRB | P24530 | 1/20 | 0.36 |
| ▸ | CCR8 | P51685 | 3/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4086401 | 0.81 | SERPINE1 (0.39) | SERPINE1PTGESPPARG | |
| SCHEMBL6091753 | 0.75 | SERPINE1 (0.57) | FAAHSERPINE1PTGESFABP1PPARG | |
| SCHEMBL6091399 | 0.71 | SERPINE1 (0.46) | FAAHSERPINE1PTGESFABP1PPARG | |
| SCHEMBL6090004 | 0.70 | CCR8 (0.43) | FAAHSERPINE1FABP1PPARGCCR8 | |
| SCHEMBL6092494 | 0.68 | SERPINE1 (0.47) | FAAHSERPINE1FABP1PPARGCCR8 | |
| SCHEMBL6856145 | 0.65 | EDNRB (0.41) | SERPINE1EDNRBKDM4EALDH1A1LMNA | |
| SCHEMBL2808240 | 0.63 | SERPINE1 (0.57) | SERPINE1PPARGEDNRBNR4A1NR4A2 | |
| SCHEMBL2810203 | 0.62 | SERPINE1 (0.62) | SERPINE1PPARGEDNRB | |
| SCHEMBL2807015 | 0.62 | SERPINE1 (0.62) | SERPINE1PTGESPPARGEDNRBALOX5 | |
| SCHEMBL13802648 | 0.61 | FAAH (0.49) | FAAHKDM4EALDH1A1SMN1; SMN2NR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069384-A1 | THIENOPYRROLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069384-A1 | THIENOPYRROLES USEFUL IN THE TREATMENT OF INFLAMMATION | NPY5R, TH, PTGES | FAAH 4639/4885SERPINE1 1731/4885PTGES 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.