Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CMA1 | P23946 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3580890 | 0.83 | LMNA (0.42) | ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL3592958 | 0.78 | MAPK14 (0.45) | ALDH1A1TSHRSMN1; SMN2HPGDMEN1 | |
| SCHEMBL3581370 | 0.77 | PDE10A (0.37) | ROCK2CMA1CTSKNPBWR1 | |
| SCHEMBL3589496 | 0.76 | MAPT (0.43) | MEN1KMT2AROCK2TP53NPBWR1 | |
| SCHEMBL3577324 | 0.75 | SMN1; SMN2 (0.42) | ALDH1A1SMN1; SMN2ROCK2POLBL3MBTL1 | |
| SCHEMBL3577788 | 0.72 | ROCK2 (0.45) | ROCK2P2RX7 | |
| SCHEMBL3590298 | 0.72 | MAPK1 (0.49) | TP53P2RX7 | |
| SCHEMBL3588015 | 0.72 | PKM (0.42) | ALDH1A1TSHRKMT2AROCK2POLB | |
| SCHEMBL3580070 | 0.70 | GPBAR1 (0.40) | TSHRHSD17B10POLBCTSKNPBWR1 | |
| SCHEMBL3588105 | 0.70 | ROCK2 (0.41) | MEN1KMT2AROCK2TP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2104670-A2 | NOVEL TRIAZINEDIONE DERIVATIVES AS GABA-B RECEPTOR MODULATORS | Addex Pharma SA (CH) | 2009-09-30 | — | — | EP | disclosed |
| WO-2008056257-A2 | NOVEL TRIAZINEDIONE DERIVATIVES AS GABA-B RECEPTOR MODULATORS | ADDEX PHARMA S.A (CH) | 2008-05-15 | — | — | WO | disclosed |