SCHEMBL4096642

SCHEMBL4096642

COc1ccc(C(=O)c2ccc(OCc3nc(-c4ccccc4)oc3C)nc2)c(OCc2ccccc2)c1

nearest known ligand 0.53

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.53
PTPN2 P17706 1/20 0.49
PTPN1 P18031 1/20 0.49
FFAR1 O14842 1/20 0.49
KDR P35968 1/20 0.48
TP53 P04637 3/20 0.47
PPARG P37231 8/20 0.47
PPARA Q07869 8/20 0.47
POLB P06746 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4104255 0.94 PPARG (0.55) PTPN2PTPN1PPARGPPARA
SCHEMBL4106336 0.90 MAPT (0.54) MAPTFFAR1KDRTP53PPARG
SCHEMBL4103337 0.89 PPARG (0.57) MAPTFFAR1TP53PPARGPPARA
SCHEMBL4092567 0.89 PPARG (0.57) MAPTFFAR1TP53PPARGPPARA
SCHEMBL4111694 0.86 MAPT (0.48) MAPTFFAR1TP53PPARGPPARA
SCHEMBL4101949 0.83 PPARG (0.57) PPARGPPARA
SCHEMBL4107823 0.83 FFAR1 (0.55) MAPTPTPN2PTPN1FFAR1KDR
SCHEMBL4100506 0.82 FFAR1 (0.60) MAPTFFAR1KDRTP53PPARG
SCHEMBL4092427 0.82 MAPT (0.61) MAPTFFAR1KDRTP53PPARG
SCHEMBL4109852 0.82 MAPT (0.61) MAPTFFAR1KDRTP53PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090054435-A1 Phenoxyalkanoic Acid Compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-02-26 US disclosed
EP-1911738-A1 PHENOXYALKANOIC ACID COMPOUND Takeda Pharmaceutical Company Limited (JP) 2008-04-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054435-A1 Phenoxyalkanoic Acid Compound PNLIP, GPR119, LIPC MAPT 3533/4885PTPN2 393/4885PTPN1 188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.