Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.62 |
| ▸ | F2 | P00734 | 6/20 | 0.62 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.62 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4096651 | 1.00 | F10 (0.62) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL4348658 | 0.77 | F10 (0.85) | F10F2PRSS1 | |
| SCHEMBL4352253 | 0.73 | F10 (1.00) | F10F2PRSS1 | |
| SCHEMBL4352256 | 0.73 | F10 (1.00) | F10F2PRSS1 | |
| SCHEMBL6244728 | 0.71 | F10 (0.57) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6185772 | 0.69 | ALOX5AP (0.51) | F10F2PRSS1 | |
| SCHEMBL9045763 | 0.67 | PTGS2 (0.52) | F10 | |
| SCHEMBL6565553 | 0.66 | F10 (0.55) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8350056 | 0.66 | CA1 (0.54) | — | |
| SCHEMBL890751 | 0.65 | F10 (0.59) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2061439-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A PLURALITY OF MINI-TABLETS COMPRISING A FACTOR XA INHIBITOR | Glaxo Group Limited (GB) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008031782-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A PLURALITY OF MINI-TABLETS COMPRISING A FACTOR XA INHIBITOR | GLAXO GROUP LIMITED (GB) | 2008-03-20 | — | — | WO | disclosed |