Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CDC25B | P30305 | 1/20 | 0.52 |
| ▸ | CASP6 | P55212 | 1/20 | 0.52 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.52 |
| ▸ | IKBKB | O14920 | 2/20 | 0.49 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.44 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20670595 | 0.85 | ALDH1A1 (0.54) | ALDH1A1HSD17B10KDM4EMAPTGAA | |
| SCHEMBL648210 | 0.85 | ALDH1A1 (0.72) | ALDH1A1HSD17B10KDM4EMAPTGAA | |
| SCHEMBL24574268 | 0.84 | ALDH1A1 (0.71) | ALDH1A1HSD17B10KDM4EMAPTGAA | |
| SCHEMBL29700063 | 0.84 | ALDH1A1 (0.71) | ALDH1A1HSD17B10KDM4EMAPTGAA | |
| SCHEMBL10818516 | 0.84 | IKBKB (0.45) | ALDH1A1HSD17B10KDM4EMAPTGAA | |
| SCHEMBL9041416 | 0.83 | ALDH1A1 (0.53) | ALDH1A1HSD17B10KDM4EMAPTGAA | |
| SCHEMBL22445528 | 0.82 | ALDH1A1 (0.53) | ALDH1A1HSD17B10KDM4EMAPTGAA | |
| SCHEMBL27663595 | 0.82 | ALDH1A1 (0.53) | ALDH1A1HSD17B10KDM4EMAPTGAA | |
| SCHEMBL221403 | 0.81 | ALDH1A1 (0.81) | ALDH1A1HSD17B10KDM4EMAPTGAA | |
| SCHEMBL17058417 | 0.81 | ALDH1A1 (0.52) | ALDH1A1HSD17B10KDM4EMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105198786-A | Aryl-substituted amide compound, preparing method thereof, medicine composition comprising same, and application thereof | INST MED BIOTECHNOLOGY CAMS | 2015-12-30 | — | — | CN | disclosed |
| US-20090209536-A1 | AMINOQUINAZOLINE CANNABINOID RECEPTOR MODULATORS FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-08-20 | — | — | US | disclosed |
| WO-2008157500-A1 | AMINOQUINAZOLINE CANNABINOID RECEPTOR MODULATORS FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2008-12-24 | — | — | WO | disclosed |
| US-7429604-B2 | Six-membered heterocycles useful as serine protease inhibitors | BRISTOL MYERS SQUIBB COMPANY (US) | 2008-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209536-A1 | AMINOQUINAZOLINE CANNABINOID RECEPTOR MODULATORS FOR TREATMENT OF DISEASE | CNR2, CNR1, GPR18 | ALDH1A1 4857/4885HSD17B10 4195/4885KDM4E 1626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.