Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | CDC25B | P30305 | 1/20 | 0.72 |
| ▸ | CASP6 | P55212 | 1/20 | 0.72 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7018271 | 0.85 | ALDH1A1 (0.68) | ALDH1A1CDC25BCASP6RCE1KDM4E | |
| SCHEMBL1685286 | 0.85 | ALDH1A1 (0.52) | ALDH1A1CDC25BCASP6RCE1KDM4E | |
| SCHEMBL4097033 | 0.85 | ALDH1A1 (0.54) | ALDH1A1CDC25BCASP6RCE1KDM4E | |
| SCHEMBL20670595 | 0.85 | ALDH1A1 (0.54) | ALDH1A1CDC25BCASP6RCE1KDM4E | |
| SCHEMBL25170829 | 0.84 | ALDH1A1 (0.78) | ALDH1A1CDC25BCASP6RCE1KDM4E | |
| SCHEMBL30291197 | 0.84 | ALDH1A1 (0.78) | ALDH1A1CDC25BCASP6RCE1KDM4E | |
| SCHEMBL29861837 | 0.84 | ALDH1A1 (1.00) | ALDH1A1CDC25BCASP6RCE1KDM4E | |
| SCHEMBL107442 | 0.84 | ALDH1A1 (1.00) | ALDH1A1CDC25BCASP6RCE1KDM4E | |
| SCHEMBL29832194 | 0.84 | ALDH1A1 (1.00) | ALDH1A1CDC25BCASP6RCE1KDM4E | |
| SCHEMBL9041416 | 0.83 | ALDH1A1 (0.53) | ALDH1A1CDC25BCASP6RCE1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250026769-A1 | PAPD5 INHIBITORS AND METHODS OF USE THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2025-01-23 | — | — | US | disclosed |
| EP-4423081-A2 | PAPD5 INHIBITORS AND METHODS OF USE THEREOF | The Children's Medical Center Corporation (US) | 2024-09-04 | — | — | EP | disclosed |
| CN-118201920-A | PAPD5 inhibitors and methods of use thereof | 儿童医疗中心公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-118176259-A | Dispersion of carbon nanotubes, coating liquid composition for electrode using same, electrode, and lithium ion secondary battery | 第一工业制药株式会社 | 2024-06-11 | — | — | CN | disclosed |
| CN-118043733-A | Polymer dispersed liquid crystal element and method for manufacturing same | 日产化学株式会社 | 2024-05-14 | — | — | CN | disclosed |
| WO-2023086220-A2 | PAPD5 INHIBITORS AND METHODS OF USE THEREOF | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2023-05-19 | — | — | WO | disclosed |
| WO-2023086220-A2 | PAPD5 INHIBITORS AND METHODS OF USE THEREOF | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2023-05-19 | — | — | WO | disclosed |
| CN-111690321-B | Varnish for photo-alignment film and liquid crystal display device | 株式会社日本显示器 | 2022-02-08 | — | — | CN | disclosed |
| CN-111690321-A | Varnish for photo-alignment film and liquid crystal display device | 株式会社日本显示器 | 2020-09-22 | — | — | CN | disclosed |
| US-20190300509-A1 | MODULATORS OF SOCE, COMPOSITIONS, AND USES THEREOF | UNIVERSITA DEGLI STUDI DEL PIEMONTE ORIENTALE "AMEDEO AVOGADRO" (IT) | 2019-10-03 | — | — | US | disclosed |
| US-6291523-B1 | SELECTIVE COX-2 CYCLOOXYGENASE INHIBITORS | NOVARTIS AG (CH) | 2001-09-18 | — | — | US | disclosed |
| CN-1268112-A | Certain 5-alkyl-2-arylaminophenylacetic acids and derivatives thereof | NOVARTIS AG (CH) | 2000-09-27 | — | — | CN | disclosed |
| EP-1007505-A1 | CERTAIN 5-ALKYL-2-ARYLAMINOPHENYLACETIC ACIDS AND DERIVATIVES | Novartis AG (CH) | 2000-06-14 | — | — | EP | disclosed |
| WO-1999011605-A1 | CERTAIN 5-ALKYL-2-ARYLAMINOPHENYLACETIC ACIDS AND DERIVATIVES | NOVARTIS AG (CH) | 1999-03-11 | — | — | WO | disclosed |
| US-4673631-A | OF AN AMINO ACID COMPOUND | CANON KABUSHIKI KAISHA (JP) | 1987-06-16 | — | — | US | disclosed |
| US-4543356-A | Quinazoline derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-09-24 | — | — | US | disclosed |
| EP-0030156-B1 | QUINAZOLINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-21 | — | — | EP | disclosed |
| US-4429126-A | ANTIASTHMA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-01-31 | — | — | US | disclosed |
| US-4377580-A | ANTIALLERGENIC AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-03-22 | — | — | US | disclosed |
| EP-0030156-A1 | Quinazoline derivatives, processes for their preparation and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-06-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190300509-A1 | MODULATORS OF SOCE, COMPOSITIONS, AND USES THEREOF | STIM1, ORAI1, SARAF | ALDH1A1 1839/4885CDC25B 802/4885CASP6 2179/4885 |
| US-20250026769-A1 | PAPD5 INHIBITORS AND METHODS OF USE THEREOF | POT1, PARP15, TERT | ALDH1A1 2733/4885CDC25B 2661/4885CASP6 3031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.