SCHEMBL4097536

SCHEMBL4097536

CCOC(=O)C(C)(C)Oc1ccc(C(=O)CCc2cn(-c3ccc(C)cn3)nc2C(C)C)cc1C

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 2/20 0.35
LMNA P02545 1/20 0.32
P2RY12 Q9H244 1/20 0.32
PPARG P37231 1/20 0.31
PPARA Q07869 1/20 0.31
TAS1R3 Q7RTX0 2/20 0.30
TAS1R1 Q7RTX1 2/20 0.30
THRA P10827 1/20 0.30
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4096996 0.91 PPARA (0.39) PPARGPPARA
SCHEMBL4101351 0.86 LMNA (0.35) LMNATAS1R3TAS1R1THRATHRB
SCHEMBL4100532 0.84 PTGDR2 (0.37) LMNAPPARGPPARATHRATHRB
SCHEMBL4095608 0.83 PPARD (0.38) FBP1PPARGPPARA
SCHEMBL4105051 0.81 ALPG (0.34)
SCHEMBL4108779 0.74 PPARD (0.46) PPARGPPARA
SCHEMBL2467843 0.73 PPARD (0.45) FBP1LMNAP2RY12PPARGPPARA
SCHEMBL4098493 0.71 PPARD (0.40) PPARGPPARA
SCHEMBL5187932 0.69 FBP1 (0.55) FBP1PPARGPPARATAS1R3TAS1R1
SCHEMBL6035631 0.69 CYP4F2 (0.38) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090240058-A1 Activator for Peroxisome Proliferator-Activating Receptor Delta NIPPON CHEMIPHAR CO., LTD. (JP) 2009-09-24 US disclosed
EP-1854784-A1 ACTIVATOR FOR PEROXISOME PROLIFERATOR ACTIVATING RECEPTOR Nippon Chemiphar Co., Ltd. (JP) 2007-11-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090240058-A1 Activator for Peroxisome Proliferator-Activating Receptor Delta PPARG, PPARA, PPARD FBP1 2629/4885LMNA 3213/4885P2RY12 417/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.