Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.59 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.52 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | GMNN | O75496 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | BLM | P54132 | 2/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | CMKLR1 | Q99788 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7382226 | 0.82 | DRD4 (0.65) | DRD4 | |
| SCHEMBL4097494 | 0.80 | CYP1A2 (0.42) | PTPN1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL22502969 | 0.79 | KDM2B (0.45) | PTPN1NR4A1NR4A2NR4A3ALDH1A1 | |
| SCHEMBL29457006 | 0.77 | PTPN1 (0.71) | PTPN1NR4A1NR4A2NR4A3ALDH1A1 | |
| SCHEMBL5857951 | 0.77 | PTPN1 (0.71) | PTPN1NR4A1NR4A2NR4A3ALDH1A1 | |
| SCHEMBL31591716 | 0.77 | ALDH1A1 (0.54) | PTPN1ALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL9701408 | 0.77 | PTPN1 (0.65) | PTPN1NR4A1NR4A2NR4A3ALDH1A1 | |
| SCHEMBL1448941 | 0.76 | PTPN1 (0.69) | PTPN1NR4A1NR4A2NR4A3ALDH1A1 | |
| SCHEMBL11713079 | 0.76 | PTPN1 (0.69) | PTPN1NR4A1NR4A2NR4A3ALDH1A1 | |
| SCHEMBL30375866 | 0.76 | PTPN1 (0.69) | PTPN1NR4A1NR4A2NR4A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221645-A1 | Dihydroimidazothiazole Derivatives | PROSIDION LIMITED (GB) | 2009-09-03 | — | — | US | disclosed |
| US-20090221645-A1 | Dihydroimidazothiazole Derivatives | PROSIDION LIMITED (GB) | 2009-09-03 | — | — | US | disclosed |
| US-20090221645-A1 | Dihydroimidazothiazole Derivatives | PROSIDION LIMITED (GB) | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221645-A1 | Dihydroimidazothiazole Derivatives | TPH1, HTR3B, HTR1A | PTPN1 2958/4885NR4A1 498/4885NR4A2 544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.