Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 7/20 | 0.39 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3C2A | O00443 | 1/20 | 0.37 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.37 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.37 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4097894 | 1.00 | PTK2 (0.39) | PTK2DYRK3AURKAAURKBMAPK14 | |
| SCHEMBL3642199 | 0.95 | PTK2 (0.40) | PTK2DYRK3AURKAAURKBMAPK14 | |
| SCHEMBL3642201 | 0.95 | PTK2 (0.40) | PTK2DYRK3AURKAAURKBMAPK14 | |
| Trifluoroacetic Acid SCHEMBL4096273 | 0.91 | DYRK3 (0.38) | PTK2DYRK3MAPK14DRD2HTR2A | |
| Trifluoroacetic Acid SCHEMBL4096267 | 0.91 | DYRK3 (0.38) | PTK2DYRK3MAPK14DRD2HTR2A | |
| Trifluoroacetic Acid SCHEMBL4094711 | 0.88 | L3MBTL1 (0.42) | DYRK3PIK3CDPIK3CAPIK3CGKDM4E | |
| Trifluoroacetic Acid SCHEMBL4094715 | 0.88 | L3MBTL1 (0.42) | DYRK3PIK3CDPIK3CAPIK3CGKDM4E | |
| Trifluoroacetic Acid SCHEMBL4084120 | 0.87 | DRD3 (0.46) | DRD2HTR2ADRD3KDM4EALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL4084123 | 0.87 | DRD3 (0.46) | DRD2HTR2ADRD3KDM4EALDH1A1 | |
| SCHEMBL2995664 | 0.86 | DYRK3 (0.41) | PTK2DYRK3AURKAAURKBMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203692-A1 | NOVEL CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203692-A1 | NOVEL CHEMICAL COMPOUNDS | HIPK3, HIPK1, HIPK4 | PTK2 144/4885DYRK3 1471/4885AURKA 2222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.