Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | GPR6 | P46095 | 2/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4094715 | 1.00 | L3MBTL1 (0.42) | L3MBTL1ENPP2DYRK3CDK5CDK5R1 | |
| SCHEMBL2995872 | 0.95 | ENPP2 (0.43) | ENPP2DYRK3CDK5CDK5R1ALDH1A1 | |
| SCHEMBL2995870 | 0.95 | ENPP2 (0.43) | ENPP2DYRK3CDK5CDK5R1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL4090187 | 0.92 | DYRK3 (0.39) | DYRK3NLRP3PIK3CDPIM1CSNK2A2 | |
| Trifluoroacetic Acid SCHEMBL4090191 | 0.92 | DYRK3 (0.39) | DYRK3NLRP3PIK3CDPIM1CSNK2A2 | |
| Trifluoroacetic Acid SCHEMBL4102474 | 0.89 | HPGD (0.37) | ENPP2DYRK3GPR6PIK3CDPIM1 | |
| Trifluoroacetic Acid SCHEMBL4102468 | 0.89 | HPGD (0.37) | ENPP2DYRK3GPR6PIK3CDPIM1 | |
| Trifluoroacetic Acid SCHEMBL4087964 | 0.89 | CCR3 (0.38) | DYRK3GPR6CCR3 | |
| Trifluoroacetic Acid SCHEMBL4087957 | 0.89 | CCR3 (0.38) | DYRK3GPR6CCR3 | |
| Trifluoroacetic Acid SCHEMBL4097884 | 0.88 | PTK2 (0.39) | DYRK3ALDH1A1KDM4EPIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203692-A1 | NOVEL CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203692-A1 | NOVEL CHEMICAL COMPOUNDS | HIPK3, HIPK1, HIPK4 | L3MBTL1 611/4885ENPP2 954/4885DYRK3 1471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.