Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 6/20 | 0.56 |
| ▸ | CYP1B1 | Q16678 | 6/20 | 0.56 |
| ▸ | MAOB | P27338 | 3/20 | 0.56 |
| ▸ | GPR183 | P32249 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | PTAFR | P25105 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4097921 | 1.00 | CYP1A1 (0.56) | CYP1A1CYP1B1MAOBGPR183NR4A1 | |
| SCHEMBL4097918 | 1.00 | CYP1A1 (0.56) | CYP1A1CYP1B1MAOBGPR183NR4A1 | |
| SCHEMBL3940795 | 0.89 | THRB (0.54) | CYP1B1MAOBTHRBATMMAPT | |
| SCHEMBL3940784 | 0.89 | THRB (0.54) | CYP1B1MAOBTHRBATMMAPT | |
| SCHEMBL3939191 | 0.89 | NR4A1 (0.51) | CYP1A1CYP1B1MAOBNR4A1NR4A2 | |
| SCHEMBL3939194 | 0.89 | NR4A1 (0.51) | CYP1A1CYP1B1MAOBNR4A1NR4A2 | |
| SCHEMBL3942285 | 0.88 | CYP1A1 (0.48) | CYP1A1CYP1B1MAOBKDRPTAFR | |
| SCHEMBL3942276 | 0.88 | CYP1A1 (0.48) | CYP1A1CYP1B1MAOBKDRPTAFR | |
| SCHEMBL3942282 | 0.88 | CYP1A1 (0.48) | CYP1A1CYP1B1MAOBKDRPTAFR | |
| SCHEMBL3940772 | 0.87 | NR4A1 (0.43) | CYP1A1CYP1B1MAOBNR4A1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203667-A1 | PENTADIENAMIDE DERIVATIVES | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203667-A1 | PENTADIENAMIDE DERIVATIVES | PRMT1, REN, NGLY1 | CYP1A1 916/4885CYP1B1 382/4885MAOB 747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.